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Primary carcinoma of the gallbladder: staging, methods of treatment and prognosis

, : Primary carcinoma of the gallbladder: staging, methods of treatment and prognosis. Taiwan Yi Xue Hui Za Zhi. Journal of the Formosan Medical Association 86(9): 947-951

In order to study the prognostic factors of gallbladder cancer, we evaluated the prognosic significance of the disease stage, methods of treatment, and histologic features in 31 patients with histologically proven primary carcinoma of the gallbladder in the past 10 years. There were 14 males and 17 females. More than 2/3 (21 cases) were aged 60 years or more. The symptoms and signs were non-specific, and the duration of symptoms shorter than one year in most cases. Apart from 6 non-operated cases, a correct preoperative diagnosis was made in only 7 cases (27%). The histological type was adenocarcinoma in all the 31 patients and in 6 of them the tumor was papillary in type. Gallstones were found in 19 cases (61%). Fourteen patients received definite procedures including curative cholecystectomy in 12 (incidental, 7) and cholecystectomy with additional major hepatectomy in 2. The most important factors deciding the prognosis were the Nevin stage of cancer invasion and the histological type of cancer. The role of aggressive surgical teratment remains obscure.


PMID: 3694166

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