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Prognostic parameters in myelodysplastic syndromes a multiple regression analysis

, : Prognostic parameters in myelodysplastic syndromes a multiple regression analysis. European Journal of Haematology 40(2): 158-162

The influence on survival of 21 basic clinical and hematologic parameters was evaluated in 72 patients with previously untreated myelodysplastic syndromes (MDS). Only five parameters were significantly by both survival curves and multiple regression analyses: hemoglobin level, bone marrow (BM) cellularity (estimated from trephine BM biopsies), BM blast percentage, age and BM erythro/myeloid (E/M) ratio. Using these parameters, multiple regression enabled us to predict 34% of the survival of all MDS patients (p < 0.002), 38% of that of patients who had stable disease (p < 0.04) and over 80% of that of patients who developed acute leukemia (p < 0.02). High BM cellularity was the most predictive factor for the development of leukemia. No factor was predictive for patients who died of cytopenic or other complications.


PMID: 3345829

DOI: 10.1111/j.1600-0609.1988.tb00814.x

Other references

Rosenberg M.E., 1989: Protective device for hypodermic needle us patent 4857060 august 15 1989. Official Gazette of the United States Patent & Trademark Office Patents 1105(3): 1713

Lintern, S., 2013: Fears over use of HCA apprentices. Nursing Times 109(14): 2-3

Heit, S.; Graham, Y.; Nemeroff, C.B., 1999: Neurobiological effects of early trauma. Harvard Mental Health Letter 16(4): 4-6

Polson, H.E.J.; de Lartigue, J.; Rigden, D.J.; Reedijk, M.; Urbé, S.; Clague, M.J.; Tooze, S.A., 2013: Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagosome formation is a complex process that begins with the nucleation of a pre-autophagosomal structure (PAS) that expands into a phagophore or isolation membrane, the precursor of the autophagosome. A key event in the formation of the phag...

Jackson, W.F., 1986: Prostaglandins do not mediate arteriolar oxygen reactivity. The hypothesis that prostaglandins mediate arteriolar O2 reactivity was tested by assessing the effects of cyclooxygenase and phospholipase A2 inhibitors on the O2 responses of arterioles in superfused hamster cheek and pouch and hamster and rat c...

Tanaka, H.; Kojima, S.; Yatazawa, M., 1965: Bioassay of boron. 2. Determining available boron in soils by Lemna pausicostata. Multiplication of Lemna pausicostata was constant under 4500 lux continuous illumination using a daylight fluorescent lamp, 28 degrees C temperature, 40-200 ppm N, 20-200 ppm P, 10-20 ppm K, 40-200 ppm Ca, 10-150 ppm Mg and pH 6.2-7.8. Under these...

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TenBrink, Joe., 1993: Mountain plovers (Charadrius montanus) nesting north of Byers, Colorado. C.F.O. Journal. October; 274: 165-166