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Species nonspecific fraction of nonhistone chromatin proteins in mice and rats immunized with bacterial lipo poly saccharides

, : Species nonspecific fraction of nonhistone chromatin proteins in mice and rats immunized with bacterial lipo poly saccharides. Molecular & Cellular Biochemistry 37(1): 21-26

In the chromatin of spleen cells of mice and rats immunized with lipopolysaccharides from Escherichia coli, a new species and antigen nonspecific fraction of non-histone chromatin proteins is described. The possible role of this fraction in the regulatory process of gene activation during the immune response as expressed by the synthesis of the IgM class of antibodies is discussed.


PMID: 7019666

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