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Synthesis and anti helminthic activity of 2 n 4 substituted n 1 piperazinyl methyl 5 or 6 substituted benzimidazoles


, : Synthesis and anti helminthic activity of 2 n 4 substituted n 1 piperazinyl methyl 5 or 6 substituted benzimidazoles. Bulletin of Haffkine Institute 6(2): 62-64

A series of substituted piperazinomethyl benzimidazoles were prepared and tested for in vivo anthelmintic activity. The majority of the compounds showed activity above 80% at 500 mg/kg dose as compared to Yomesan, showing 100% activity at 500 mg/kg dose. The results confirm the importance of the nitro group in the benzimidazole ring for anthelmintic activity.

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