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Synthesis and properties of hexanucleotides containing deoxyinosine

, : Synthesis and properties of hexanucleotides containing deoxyinosine. Chemical & Pharmaceutical Bulletin (Tokyo) 36(1): 118-121

Self-complementary hexanucleotides d(GGINCC) (N = C, A, G, T) were synthesized by the phosphotriester method. The circular dichroism (CD) spectra of these oligonucleotides showed that the oligonucleotides containing I:C or I:A pairs seem to possess a shape similar to deoxyribonucleic acid (DNA) with right-handed stacking.


DOI: 10.1248/cpb.36.118

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