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The genetic effects of crocidolite asbestos comparison of chromosome abnormalities and sister chromatid exchanges


, : The genetic effects of crocidolite asbestos comparison of chromosome abnormalities and sister chromatid exchanges. Mutation Research 79(4): 331-336

The genetic effects of crocidolite asbestos in Chinese hamster lung V79-4 cells are compared with those of potassium chromate and Min-u-Sil silica. Potassium chromate, a known mutagen, increased the frequency of SCE [sister chromatid exchanges]. Neither crocidolite nor silica induced SCE, even though crocidolite caused numerical changes in the karyotype. [The carcinogenicity of crocidolite asbestos was also discussed].

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