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The Manx cat: an animal model for neural tube defects


, : The Manx cat: an animal model for neural tube defects. Materia Medica Polona. Polish Journal of Medicine and Pharmacy 19(4): 219-221

Basic knowledge about the aetiology and pathogenesis of spina bifida and other neural tube defects in man is lacking. The Manx cat is a tail-less variant of the common domestic cat which exhibits a heritable form of neural tube defect which can present with a broad spectrum of clinical pictures, including spina bifida. A kindred of Manx cats is presented here in which some individuals were conceived and born in the Isle of Man, and others were conceived and born in the West of Scotland. The pedigree of the kindred suggests that the overwhelmingly important factor in the production of the tail-less, or "Manx" trait, is a single autosomal dominant gene for the trait, and it is suggested that the Manx cat may be a suitable animal model for studies into the aetiology and pathogenesis of spina bifida and other neural tube defects.

US$29.90

PMID: 3454827


Other references

Reuter, Cézane.Priscila.; Burgos, L.Tibiriçá.; Camargo, M.Dias.; Possuelo, L.Gonçalves.; Reckziegel, M.Beatris.; Reuter, Éboni.Marília.; Meinhardt, F.Pasqualotti.; Burgos, M.Suzana., 2014: Prevalence of obesity and cardiovascular risk among children and adolescents in the municipality of Santa Cruz do Sul, Rio Grande do Sul. Studies have demonstrated that metabolic complications from child obesity, although silent, increase the risk of development of cardiovascular diseases in adulthood. The present paper sought to describe the prevalence of overweight/obesity and ana...

Weller C.; Lewis M.F., 1976: The role of surface acoustic waves and ir communications in bio telemetry. Biotelemetry 3(1): 56-57

Osma, U.; Cureoglu, S.; Yaldiz, M.; Topcu, I., 2001: Castleman's disease (giant lymph node hyperplasia) of the neck: A case report. Castleman's disease (giant lymph node hyperplasia) is an uncommon cause of neck mass. Its cause and pathogenesis are still unknown. Giant lymph node hyperplasia (GLH) usually presents as an asymptomatic solitary mass and can occur anywhere in...

Françon, F.; Diaz, R., 1972: Fracture-related painful reaction during the Aix-les-Bains cure. Rhumatologie 24(10): 397-398

Anderson, H.; Lind, M.J.; Thatcher, N.; Swindell, R.; Woodcock, A.; Carroll, K.B., 1990: Therapy for poor-risk patients with small-cell lung cancer using bolus ifosfamide and oral etoposide. A total of 47 poor-risk small-cell lung cancer patients (elderly, poor performance status, recent myocardial infarction, or extensive-stage disease with biochemical abnormalities) were treated with a regimen of bolus ifosfamide at 1.5 g/m2 with eq...

Braga, J.M., 1961: The children in my files. Revista Brasileira de Medicina 18: 757-757

Bean, J.; Smith, B.; Crosby, R., 1979: Two nurse practitioner experiences. Rn Idaho 3(4): 4-4

Leng, Y-xin.; Wei, Y-yu.; Zhou, S-pei.; Duan, L-ping., 2010: Establishment of irritable bowel syndrome rat model by combination of intestinal infection with Trichinella spiralis and acute stress. To establish the irritable bowel syndrome (IBS) rat model by the combination of acute stress and transient intestinal infection with Trichinella spiralis (T.S.). The rat model of acute cold restraint stress post-infection (PI + ACRS) was establish...

Lamy L.; Lamy H., 1970: Intra cellular transformation of amastigote forms of trypanosoma cruzi and leishmania into mastigote forms. Journal of Protozoology 17(SUPPL): 35-36

Khamboonruang, C., 1991: On emerging problems in food-borne parasitic zoonosis: impact on agriculture and public health. Southeast Asian Journal of Tropical Medicine and Public Health 22 Suppl: 1-7