geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Use of the maximal st hr slope to estimate myocardial ischemia after recent myocardial infarction


, : Use of the maximal st hr slope to estimate myocardial ischemia after recent myocardial infarction. British Heart Journal 57(6): 512-520

Fifty two patients were examined 4-6 weeks after myocardial infarction to assess whether factors other than coronary artery narrowing affect the maximal ST/HR slope which is used as an index of myocardial ischaemia. The slope was compared with indices of myocardial scarring or cardiac enlargement derived from X-ray and echocardiographic and angiocardiographic investigations. In 35 (67%) patients the slope failed to predict the severity of myocardial ischaemia attributable to coronary artery narrowing: in 14 (27%) patients the slope overestimated the findings of coronary angiography and in 21 (40%) patients the slope underestimated the findings of coronary angiography. In the remaining 17 (33%) patients the slope accorded with the assessment of myocardial ischaemia by coronary angiography. Underestimation by the slope was associated with significantly poorer left ventricular function and a lower ejection fraction, indicating a greater degree of myocardial scarring. To assess whether overestimation was related to cardiac enlargement with better preservation of ventricular function a follow up examination was performed six months after infarction. In the overestimated group 11 patients were followed up and seven of them showed a reduction in the maximal ST/HR slope which correlated with a reduction in the cardiothoracic ration. This suggested that cardiac enlargement had contributed to myocardial ischaemia. The results suggest that if the maximal ST/HR slope is an index of exercise induced myocardial ischaemia after recent infarction, it is subject to the influences of coronary artery narrowing as well as those of scarring and cardiac enlargement.

US$29.90

PMID: 3620227


Other references

V.Z.Kisel’nikova, 2013: Object-based evaluation of precipitation forecast quality. The method of object-based diagnostic evaluation (MODE) is used to estimate the quality of forecasts of intensive precipitation zones using the WRF-ARW mesoscale nonhydrostatic model. The model is integrated on the horizontal 3-km grid without the...

Schulz Rojahn J.P.; Stuart W.J., 1991: Controls on porosity and permeability distribution in the southern Cooper Basin, Australia; implications for petroleum exploration. AAPG Bulletin 75(3): 669

Ueha, S.; Yoneyama, H.; Hontsu, S.; Kurachi, M.; Kitabatake, M.; Abe, J.; Yoshie, O.; Shibayama, S.; Sugiyama, T.; Matsushima, K., 2007: CCR7 mediates the migration of Foxp3+ regulatory T cells to the paracortical areas of peripheral lymph nodes through high endothelial venules. Thymus-derived forkhead box p3(+) naturally occurring regulatory T cells (nTreg) are thought to circulate throughout the body to maintain peripheral immunological self-tolerance through interactions with dendritic cells (DCs), resulting in regula...

Wong, E.D.; Wagner, J.A.; Scott, S.V.; Okreglak, V.; Holewinske, T.J.; Cassidy-Stone, A.; Nunnari, J., 2003: The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. A balance between fission and fusion events determines the morphology of mitochondria. In yeast, mitochondrial fission is regulated by the outer membrane-associated dynamin-related GTPase, Dnm1p. Mitochondrial fusion requires two integral outer me...

Dann, O.N.ckel, P.H.ttche, H.S.euding, W.F.nk, E., 1981: Antimalarial 6-aminoquinolines. XIII. 5,8-Dialkoxy derivatives of 6-(4-diethylamino-1-methylbutylamino)-2-methyl- and 6-(4-diethylamino-1-methylbutylamino)-2,4-dimethylquinoline. Plasmodium vinckei, mice, antimalarial activity and toxicity of several 6-aminoquinolines

Adelson, M.E.; Pacchia, A.L.; Kaul, M.; Rando, R.F.; Ron, Y.; Peltz, S.W.; Dougherty, J.P., 2003: Toward the development of a virus-cell-based assay for the discovery of novel compounds against human immunodeficiency virus type 1. The emergence of human immunodeficiency virus type 1 (HIV-1) strains resistant to highly active antiretroviral therapy necessitates continued drug discovery for the treatment of HIV-1 infection. Most current drug discovery strategies focus upon a...

Fournier, K.B.; May, M.J.; Colvin, J.D.; Barrios, M.A.; Patterson, J.R.; Regan, S.P., 2013: Demonstration of a 13-keV Kr K-shell x-ray source at the National Ignition Facility. We report 3% conversion efficiency of laser energy into Kr K-shell (≈13 keV) radiation, consistent with theoretical predictions. This is ≈10× greater than previous work. The emission was produced from a 4.1-mm-diameter, 4-mm-tall gas pipe tar...

Bonnemaison, L., 1952: Morphology and biology of the cabbage ornate bug (Eurydema ventralis Kol.). The nomenclature, pigmentation, morphology, physiology, life cycle, habits, parasites and predators of the cabbage bug are discussed. Control methods suggested are crop rotation, the destruction of cruciferous weeds, the use of cardboard or metal-...

Kochevar I.E.; Walsh A.A.; Buckley L.A.; Held K.D.; Gallo R.L.; Mirro J., 1989: Cell killing and dna photochemistry using 193 nm excimer laser radiation. Photochemistry & Photobiology 49(SUPPL): 47S

Paterson, D.L.; Staplefeldt, W.H.; Wagener, M.M.; Gayowski, T.; Marino, I.R.; Singh, N., 1999: Intraoperative hypothermia is an independent risk factor for early cytomegalovirus infection in liver transplant recipients. Background. Early cytomegalovirus (CMV) reactivation infections have been found to be associated with a number of stress responses such as severe bacterial infection. Intraoperative hypothermia is known to be a significant physiological stressor....