geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Alkaloidal content and certain pharmacological activities of fumaria parviflora lam. growing in egypt


, : Alkaloidal content and certain pharmacological activities of fumaria parviflora lam. growing in egypt. Plantes Medicinales et Phytotherapie 23(2): 109-123

No qualitative variation in the alkaloidal content of the different organs of Fumaria parviflora Lam. was observed, although they varied quantitatively when assayed by non-aqueous titration. After column chromatography of extracts, protopine and another alkaloid, suggested to be the desmethyl congener of the synthetic tetrahydroescholamine were isolated. The two alkaloids were characterized by their m.ps., chromatographic behaviour as well as UV, IR, NMR and mass spectra. Toxicological and pharmacological investigation of the ethanolic extract of F. parviflora as well as the alkaloid "protopine" isolated thereof were carried out. Both exhibited a significant decrease in intestinal muscle contractions. Significant cardioinhibitory, antiarrhythmic, hypotensive and antipyretic effects were also found. The ethanolic extract of the plant as well as protopine can, thus, be used as intestinal antispasmodic, antihypertensive and antiarrhythmic.

US$29.90


Other references

Almeida, M.A.B.; Cardoso, J.da.C.; Dos Santos, E.; da Fonseca, D.F.; Cruz, L.L.; Faraco, F.J.C.; Bercini, M.A.; Vettorello, Kátia.C.; Porto, M.A.; Mohrdieck, R.; Ranieri, T.M.S.; Schermann, M.T.; Sperb, Aéa.F.; Paz, F.Z.; Nunes, Z.M.A.; Romano, A.P.M.; Costa, Z.G.; Gomes, S.L.; Flannery, B., 2014: Surveillance for yellow Fever virus in non-human primates in southern Brazil, 2001-2011: a tool for prioritizing human populations for vaccination. In Brazil, epizootics among New World monkey species may indicate circulation of yellow fever (YF) virus and provide early warning of risk to humans. Between 1999 and 2001, the southern Brazilian state of Rio Grande do Sul initiated surveillance f...

Vellenga, L.; Wensing, T.; Breukink, H.J.; Hagens, F.H., 1986: Effects of irradiated sow colostrum on some biochemical and haematological measurements in newborn piglets. Some biochemical and haematological variables were measured in piglets during the first 48 hours after birth. The piglets were reared either by the sow, or bottle-fed with colostrum (either natural or sterilised by irradiation), or a commercial mi...

Saldana, E.; Paletta, C.; Gupta, N.; Vernava, A.M.; Longo, W.E., 1996: Internal pudendal flap anoplasty for severe anal stenosis. Report of a case. A technique for introducing anoderm into the anal canal is described. An internal pudendal flap was used. This technique was totally successful in alleviating anal stenosis and maintaining fecal continence. Internal pudendal flap should be in the...

Junqueira, L.C.; Toledo, A.M., 1966: Effect of androgen, barbiturate and puromycin on the rat submaxillary serum and amylase activity. Carbamylcholine and pilocarpine promote an increase in the rat blood submaxillary gland amylase activity. This increase is depressed by a barbiturate. Puromycin,a protein synthesis inhibitor, does not depress this para-sympathoimmetic drug induced...

Hussemann, D.L.; Tanner, F.W., 1947: Relation of certain cooking procedures to staphylococcus food poisoning. American Journal of Public Health and the Nation's Health 37(11): 1407-1414

Hutton L.K.; Johnson C.E.; Pechmann J.C.; Ebel J.E.; Given J.W.; Cole D.M.; German P.T., 1980: Epicentral locations for the Homestead Valley earthquake sequence, March 15, 1979. California Geology 33(5): 110-114

Desmyter, S.; Bijttebier, S.; van Heeringen, K., 2014: The role of neuroimaging in our understanding of the suicidal brain. This paper provides a review of the literature on neuroimaging studies of suicidal behaviour, and discusses the relevance of these studies for our understanding of suicidal behaviour. Main findings from molecular imaging studies include a reduced...

Kevan, D.; KMcE., 1969: Further records of some little-known Pyrgomorphidae and Trigonopterygidae from Fiji, New Guinea and Borneo (Orthoptera: Acridoidea). Entomologist, 102: 68-69

Ward Stanley Harry, 1959: AFMAG; airborne and ground. The existence of natural magnetic fields in the audio and subaudio frequency range has been known for some time. The primary source of energy for these fields is usually considered to be distant and local thunderstorms. Because of this origin, the...

Alp, N.J.; Mussa, S.; Khoo, J.; Cai, S.; Guzlk, T.; Rockett, K.; Channon, K.M., 2003: Nitric oxide bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice. Circulation 108(17 Supplement): IV-27, October 28