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Antifertility principle of Ruta graveolens


, : Antifertility principle of Ruta graveolens. Planta Medica 55(2): 176-178

Chloroform extracts of the root, stem and leaf of Ruta graveolens L. showed significant anti-fertility activity in rats when administered intragastrically on days 1-10 post-coitum. Fractionation of the extracts led to the isolation of chalepensin as the active component with some toxicity. Time-dosing experiments demonstrated that chalepensin acts at the early stages of pregnancy. It is not clear at this stage if the anti-fertility effect is a direct manifestation of chalepensin toxicity.

US$19.90

PMID: 2748734

DOI: 10.1055/s-2006-961917


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