+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Biostatistical basis of individualisation and segregation analysis using the multilocus dna probe mz 1.3 results of a collaborative study

, : Biostatistical basis of individualisation and segregation analysis using the multilocus dna probe mz 1.3 results of a collaborative study. Forensic Science International 55(1): 45-58

A collaborative study using the multilocus minisatellite DNA probe MZ 1.3 was carried out to investigate segregation information, mutation rate, DNA fragment frequencies as well as band sharing characteristics. The fingerprint patterns of 393 children as well as 694 unrelated individuals were analysed after digestion of DNA with the restriction enzyme HinfI. A mutation rate of 1% per meiosis or 0.04% per band was found with a mean number of 26 bands/individual. It was shown that maternal and paternal fragments are inherited in equal proportions. Population frequencies of restriction fragments demonstrated a distribution with increasing frequencies in the small fragment size range below 10 kb as well as the absence of very common or very rare fragments. Our data can be used to calculate simple exclusion probabilities based on the number of non-maternal bands in the child.


PMID: 1511938

DOI: 10.1016/0379-0738(92)90093-c

Other references

Evans, R.B.; O'Connor, A., 2007: Statistics and evidence-based veterinary medicine: answers to 21 common statistical questions that arise from reading scientific manuscripts. Evidence-based veterinary medicine relies critically on the scientific validity of research. A component of validity is the statistical design and subsequent analysis of data collected during the study. Correct statistical design reduces bias and...

Marchiori F.; Borin G.; Moroder L.; Rocchi R.; Scoffone E., 1972: Relation between structure and function in some partially synthetic rnases s part 1 kinetic determinations. Biochimica et Biophysica Acta 257(2): 210-221

Takebe, I., 1974: Plant protoplasts--isolation, activity, and application. Seikagaku. Journal of Japanese Biochemical Society 46(1): 22-36

Leybourne Matthew I.; Cousens Brian L., 2005: Rare earth elements (REE) and Nd and Sr isotopes in groundwater and suspended sediments from the Bathurst Mining Camp, New Brunswick; water-rock reactions and elemental fractionation. Water Science and Technology Library 51: 253-293

Kanaly, S.T.; Hines, S.A.; Palmer, G.H., 1993: Failure of pulmonary clearance of Rhodococcus equi infection in CD4+ T-lymphocyte-deficient transgenic mice. Pulmonary clearance of Rhodococcus equi requires functional T lymphocytes. In this study, CD8+ T.lymphocyte-deficient transgenic mice cleared virulent R. equi from the lungs while infection in CD4+ T-lymphocyte-deficient transgenic mice persisted....

Srsen, S., 1968: Determination of fetal age on the basis of neurologic examination of the newborn infant. Bratislavske Lekarske Listy 50(3): 431-439

Lv, C.; Maharjan, S.; Wang, Q.; Sun, Y.; Han, X.; Wang, S.; Mao, Z.; Xin, Y.; Zhang, B., 2017: α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage. Alpha-lipoic acid (α-LA) has been demonstrated to be protective against cerebral ischemia injury. Herein, we investigate the neuroprotective effect and underlying mechanisms of α-LA. In vivo study, α-LA was administered intravenously upon reper...

Tarasevich, L.V.; Somov, G.P., 1966: Comparative serological study of tick-borne rickettsiosis occurring in northern Asia and tsutsugamushi fever. The antigenic structure of 2 causative agents (those of tick borne rickettsiosis of North Asia and of tsutsugamushi fever were subjected to a comparative serological study). Notwithstanding the presence of a common capacity to induce antibody prod...

Caprilli, R.; Paoluzi, P., 1967: The "irritable colon" syndromes. Il Policlinico. Sezione Pratica 74(50): 1696-1701

Huggins, R.A.; Deavers, S.; Smith, E.L., 1964: The circulatory effects of a homologous plasma-blood exchange in the dog. The effect on plasma and red cell volume and protein concentration of exchanging homologous plasma for the dogs' own blood before a hemorrhage to 35 mm Hg mean arterial pressure was tested in anesthetized dogs. The measured cell and plasma vo...