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Changes in plasma potassium during the dobutamine stress test


, : Changes in plasma potassium during the dobutamine stress test. International Journal of Cardiology 33(1): 55-60

We performed serial determinations of levels of potassium in 198 patients with suspected or proven coronary arterial disease who underwent a dobutamine stress test, so as to investigate if the depression in the ST segment induced by the test may be due to hypokalemia. The test consisted of an intravenous infusion of dobutamine, starting with a dose of 5 .mu.g/kg/min for 5 minutes and continuing with 10, 15, 20 and up to 40 .mu.g/kg/min every 5 minutes (mean peak dose = 20 .mu.g/kg/min). Serial 12-lead electrocardiograms were taken to detect changes in the ST segment. The double product changed with dobutamine from 8844 .+-. 6000 to 15201 .+-. 3030. The peak dose of dobutamine induced a small but significant decrease in levels of serum potassium, with a further decrease 10 minutes later. In the 198 patients, the plasma potassium changes from 4.22 .+-. 4.8 to 3.86 .+-. 0.35 mmol/I (P < 0.00001). The maximum decrease in potassium (0.56 .+-. 0.49) occurred in the patients who received the highest dose of dobutamine (30 to 40 .mu.g/kg/min). Only 17 patients reached levels lower than 3.5 mmol/l, and 4 of them achieved levels lower than 3.1 mmol/l. No correlation was found between depression of the ST segment equal to or greater than 1 mm on the electrocardiogram and the level of potassium after the test. No correlation was found between ventricular arrhythmias and levels of potassium. High doses of dobutamine, therefore, produce a small but significant decrease in potassium. As the depression of the ST segment observed on the electrocardiogram is not related to levels of potassium, it must be due to dobutamine-induced ischemia, which supports the value of the test.

US$19.90

PMID: 1937984

DOI: 10.1016/0167-5273(91)90152-f


Other references

Moriwaki Hiromu, 1992: Rapid increase of pore-water pressure during slope failure. International Geological Congress, Abstracts--Congres Geologique Internationale, Resumes 29: 937

Savard, Némie.; Bédard, L.; Allard, R.; Buckeridge, D.L., 2015: Using age, triage score, and disposition data from emergency department electronic records to improve Influenza-like illness surveillance. Markers of illness severity are increasingly captured in emergency department (ED) electronic systems, but their value for surveillance is not known. We assessed the value of age, triage score, and disposition data from ED electronic records for p...

Anonymous, 2008: The National Provider Identifier is here. Optometry 79(5): 282-284

Verniere, C., 1992: Bacterial canker of citrus (Xanthomonas campestris pv. citri). Epidemiological and ecological study on the island of Reunion. Varietal reactions of clementines, the lemon cultivar Meyer [Citrus meyeri], orange cultivar Pineapple, lime cultivar Tahiti [C. latifolia], mandarin cultivar Vangassaye and wild rutaceous species, and epidemiological and ecological aspects of the...

Dewan, Paddy A., 1996: Correlation of the endoscopic and radiological anatomy of congenital obstruction of the posterior urethra and the external sphincter. Journal of Endourology 10(SUPPL 1): S175

Vij, A.; Markus, R., 2012: Immediate vesicular eruption caused by topical 23% lidocaine 7% tetracaine ointment in a patient scheduled for laser therapy: a new adverse drug reaction. Topical anesthetic agents have increased in number, formulations, and applications because of their efficacy and generally mild side effect profile. To date, there have been no reports of immediate vesicular eruption as a result of topical applica...

Dent Brian, 1990: On the use of refracted first breaks of marine reflection data for static and dynamic corrections. Analysis of the refracted first breaks of marine reflection data can provide information on the time anomalies produced by variations in the low-velocity, near-surface sediments. However, marine data are characterized by a scatter of receiver loca...

Mizushina, Y.; Motoshima, H.; Yamaguchi, Y.; Takeuchi, T.; Hirano, K.; Sugawara, F.; Yoshida, H., 2010: 3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain. We isolated a pol inhibitor from the cultured mycelia extract of a fungal strain isolated from natural salt from a sea salt pan in Australia, which was identified as 3-O-methylfunicone by spectroscopic analyses. This compound selectively inhibited...

Balikov, B., 1957: Urobilinogen excretion in normal adults; results of assays with notes on methodology. Clinical Chemistry 3(3): 145-153

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