+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Clinicopathologic details and prognoses in patients with nodes negative colorectal cancers

, : Clinicopathologic details and prognoses in patients with nodes negative colorectal cancers. Journal of the Japan Society of Coloproctology 43(4): 583-589

In a series of 327 colorectal cancer patients surgically treated in Hiratsuka City Hospital during 1970-1989, 179 patients without regional lymph node metastasis and without distant metastasis (n(-) group were selected to compare the clinicopathologic findings and the prognosis with those in 105 patients with regional lymph node metastasis and without distant metastasis (n(+) group). The mean age of the n(-) group was significantly higher than that of the n(+) group (P < 0.05) and the proportion of male patients in the n(-) group was also significantly higher than that in the n(+) group (P < 0.05). Proportion of the cases without lymphatic vessel invasion in the n(-) group was 64.0% and was significantly higher than that in the n(+) group (P < 0.01). However, the number of patients without venous invasion was not significantly different between the two group. There was no difference in cumulative survival rate of patients in the n(-) group in respect to the background factors such as sex, tumor site, histological type, and venous invasion. However, survival rate of patients whose cancer invasion was limited within the mucosa, submucosa and proper muscle was significantly better than that of patients whose cancer extended from the mucosa beyond the proper muscle. (P < 0.01). Survival rate in patients with and without lymphatic vessel invasion was not significantly different (P < 0.05). Among patients in the n(-) group, 11 patients eventually died of recurrence. The tumor site in 9 patients was the lower rectum and the depth of invasion in these patients was beyond the proper muscle. The mean survival was 35 months. Eight patients developed distant metastasis such as lung, liver and bone. These data indicated that rectal cancers which appeared especially in the lower rectum and extended beyond the proper muscle had a high risk of recurrence among colorectal cancer patients without lymph node involvement.


Other references

Parodi, V.; de Florentiis, D.; Martini, M.; Ansaldi, F., 2011: Inactivated influenza vaccines: recent progress and implications for the elderly. The current public health strategy for the containment of influenza is annual vaccination, which is recommended for the elderly and for those in risk factor categories that present the highest morbidity and mortality. However, because the immune r...

Burden, C.; Preshaw, J.; White, P.; Draycott, T.J.; Grant, S.; Fox, R., 2014: Usability of virtual-reality simulation training in obstetric ultrasonography: a prospective cohort study. Prospective cohort study to assess the usability of virtual-reality (VR) simulation for obstetric ultrasound trainees. Twenty-six participants were recruited; 18 obstetric ultrasound trainees (with little formal ultrasonography training) and eight...

Nusbaum, A.O.; Morgello, S.; Atlas, S.W., 1999: Pial involvement in Wegener's granulomatosis shown on MRI. Involvement of the brain and meninges is rare in Wegener's granulomatosis (WG); it has been reported in 1.2-8 % of patients. Meningeal involvement in WG has been reported in imaging as being confined to the dura mater, and is thought to repre...

Rüdiger, S.; Míguez, D.G.; Muñuzuri, A.P.; Sagués, F.; Casademunt, J., 2003: Dynamics of Turing patterns under spatiotemporal forcing. We study, both theoretically and experimentally, the dynamical response of Turing patterns to a spatiotemporal forcing in the form of a traveling-wave modulation of a control parameter. We show that from strictly spatial resonance, it is possible...

Magill, M.K., 2003: Medical student clerkships and the eye of the beholder. Family Medicine 35(7): 519-521

Efthimiadis, J.; Neil, W.C.; Bunter, A.; Howlett, P.C.; Hinton, B.R.W.; MacFarlane, D.R.; Forsyth, M., 2010: Potentiostatic control of ionic liquid surface film formation on ZE41 magnesium alloy. The generation of potentially corrosion-resistant films on light metal alloys of magnesium have been investigated. Magnesium alloy, ZE41 [Mg-Zn-Rare Earth (RE)-Zr, nominal composition approximately 4 wt % Zn, approximately 1.7 wt % RE (Ce), approx...

Yashar, S.S.; Newbury, R.O.; Cunningham, B.B., 2000: Tender blue mass in an 8 year old. Pediatric Dermatology 17(3): 235-237

Priselkova, D.O.; Zorina, N.R., 1953: Shedding of the fleece in Soviet Merino sheep with infectious mastitis.. The authors studied 188 cases of shedding of the fleece during the course of infectious mastitis in ewes, caused by Bact. mastitidis ovis (Pasteurella mastitidis). Biopsy samples of skin for histological examination were taken irom 10 ewes at inte...

Aas, T.N., 1954: Simple suture in perforating ulcer. Nordisk Medicin 51(12): 407-408

Brownett, Anthony., 1992: The birds of the Slade Nature Reserve Bloxham. Unknown