+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Concurrent fast and slow synchronized efferent phrenic activities in time and frequency domain

, : Concurrent fast and slow synchronized efferent phrenic activities in time and frequency domain. Brain Research 528(1): 1-11

In urethane-anesthetized or decerebrated vagotomized rabbits efferent multifiber activity of the phrenic nerve was investigated for synchronized activities both in time and frequency domains. When respiratory drive was steadily increased by either an elevation of end-tidal CO2 concentration or i.v. administration of 4-aminopyridine, medium-frequency oscillations (MFO) first increased, then decreased and finally became absent. The power of high-frequency oscillations (HFO) steadily rose with increasing respiratory drive. In contrast to HFO which revealed a unimodal spectral peak of mostly small bandwidth, the MFO spectrum in most cases consisted of a broad complex. This complex in some cases was composed of two distinct peaks, i.e. MFO were heterogenous. The low- and high-frequency fractions of the MFO complex were related predominantly to the first and last third of inspiration, respectively. Examination of the on-going multifiber activity of the phrenic nerve with an expanded time scale revealed that lower frequency MFO probably result from synchronized ramp-like wave activity during early and mid-inspiration. The duration of the observed ramps well matched the corresponding MFO frequency. We suggest that these ramps might result from propagated synchronized waves of high-threshold phrenic motoneurons. During the last part of inspiration, however, MFO, like HFO, resulted from burst-like synchronized discharge of phrenic motoneurons. Thus HFO are superimposed on ramp-like and burst-like activity of the MFO. It is assumed that the decline of MFO at high respiratory drive may be due to the increasing strength of HFO bursts which interrupt ramp activity in the MFO range and thus let MFO appear 'invisible ' to the recording electrode. Both MFO and HFO were visually detectable in postinspiration.


PMID: 2123123

DOI: 10.1016/0006-8993(90)90187-g

Other references

Arai, T., 1971: Direct operation of the coronary artery observed at hospitals in the United States. Kyobu Geka. Japanese Journal of Thoracic Surgery 24(4): 288-291

d'Almeida, T.C.D.A.; Agboton-Zoumenou, M-Agnès.; Garcia, Aé.; Massougbodji, A.; Briand, Vérie.; Imorou, Y.; Cottrell, G., 2011: Field evaluation of the intermittent preventive treatment of malaria during pregnancy (IPTp) in Benin: evolution of the coverage rate since its implementation. Malaria is an important public health problem in Africa. Pregnant women are a vulnerable population and this disease can underlie an increased risk of low-birthweight newborns (< 25 g); these women therefore need management during pregnancy. Th...

Elkind, M.S.; Chen, X.; Boden Albala, B.; Sacco, R.L., 1998: Severe headache at stroke onset is an indicator of large vessels occlusive disease The Northern Manhattan Stroke Study. Stroke 29(1): 315, Jan

Bakos, A.; Varkonyi, A.; Minarovits, J.; Batkai, L., 2004: Effect of simulated microgravity on the production of IL-12 by PBMCs. During space flight immunity is altered. This phenomenon is partly due to the microgravity condition itself. Our earlier space experiments (INTERFERON) indicated that microgravity has a significant effect at the cellular level. In our subsequent t...

Timms, P., 1981: Inhibition of Babesia spp. by plastics. Five commercially available plastic containers [used in vaccine preparation] were compared with glass for toxicity toward B. rodhaini and B. bigemina. Comparisons were made by using infectivity tests in mice (B. rodhaini) and cattle (B. bigemina)....

Bie P., 1985: Effects of angiotensin ii on renal sodium and water excretion. Acta Physiologica Scandinavica: 38a

Maiti, S.; Maiti, P.; Sinha, S.Sekhar.; Mitra, R.Kumar.; Pal, S.Kumar., 2008: Molecular recognition of plant DNA: does it differ from conventional animal DNA?. The recognition mechanism of DNA with small drugs/ligands is an important field of research from pharmacological point of view. Such studies are ample with DNAs extracted from animal cells, but are rare for those extracted from plant cells. Howeve...

Barashko, O.G., 1987: Modelling of mixing regimes of wood particles with adhesives. The basic curve (E-function) for the distribution of residence times of wood particles in a continuous mixer was determined experimentally in a trough-shaped apparatus, into which coloured wood particles were introduced as a tracer. Equations are...

Shliapak, E.A., 1981: Delagil superdiadynamophoresis in the overall health resort therapy of children with scleroderma. Vestnik Dermatologii i Venerologii: 48-50

Schmidli, R.S.; Harrison, L.C., 1996: Glutamic acid decarboxylase autoantibodies in diabetes mellitus. Peter, J B [Editor], Shoenfeld, Y [Editor] Autoantibodies : 299-307