+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Dual role of the Drosophila pattern gene tailless in embryonic termini

, : Dual role of the Drosophila pattern gene tailless in embryonic termini. Science 254(5030): 418-421

One of the first zygotically active genes required for formation of the terminal domains of the Drosophila embryo is tailless (tll). Expression of the tll gene is activated ectopically in gain-of-function mutants of the maternal terminal gene torso (tor); this suggests that tor normally activates the tll gene in the termini. Ectopic expression of tll under the control of an inducible promoter results in differentiation of ectopic terminal-specific structures, the Filzkörper, and leads to the activation of at least one gene, hunchback, that is required to form these structures. Ectopic expression of the tll gene also represses segmentation by repressing the gap genes Krüppel and knirps and probably also pair rule genes.


PMID: 1925599

DOI: 10.1126/science.1925599

Other references

Hagelqvist, E., 1978: Light and electron microscopic studies on material obtained by fine needle biopsy. A methodological study on aspirates from tumours of the head and neck region with special emphasis on salivary gland tumours. Acta Oto-Laryngologica. Supplementum 354: 1-75

Zhang, Y.; Zhu, P.; Shi, Y.; Bu, D.; Cao, X.; Zhu, Q.; Wang, Y.; Ma, M.; Yu, J., 2003: The Experimental Study on the TCR Idiotypic DNA Vaccine to Induce Antitumor Immune Response to Lymphocytic Malignancy. This study was undertaken to investigate the anti-lymphocytic malignacy immunologic effects induced by TCR idiotypic DNA vaccine on BALB/c mice. CEM lymphoma cell line and BALB/c mice were used as models. The rearrangement gene fragment coding TCR...

Kamiide, H., 1964: Activity Of Medical Education Organizations On The Problem Of Internship. Nihon Ishikai Zasshi. Journal of the Japan Medical Association 51: 251-252

Bretelle, F.; Fenollar, F.; Baumstarck, K.; Fortanier, Cécile.; Cocallemen, J.François.; Serazin, Vérie.; Raoult, D.; Auquier, P.; Loubière, S.; Heckenroth, Hélène.; Desbriere, R.; Slim, N.; Chenni-Asselah, N.; Danoy, X.; Mauviel, F.; Bongain, Aé.; Mares, P.; Rozenberg, P.; Schmitz, T.; Benachi, A.; Marie-Victoire Senat; Haddad, B.; Ménard, J-Pierre.; Kayem, G.; Sentilhes, L.; Chauleur, Céline.; Volumenie, J-Luc.; Kadhel, P.; Fenollar, F.; Loubière, P.Auquier.Sandrine.; Fortanier, Céc, 2016: Erratum to: 'Screen-and-treat program by point-of-care of Atopobium vaginae and Gardnerella vaginalis in preventing preterm birth (AuTop trial): study protocol for a randomized controlled trial'. Trials 17: 83-83

Fischer, D.F.; van Drunen, C.M.; Winkler, G.S.; van de Putte, P.; Backendorf, C., 1998: Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker. The small proline-rich protein genes ( SPRRs ) code for precursors of the cornified cell envelope, and are specifically expressed during keratinocyte terminal differentiation. The single intron of SPRR2A enhanced the activity of the SPRR2A promote...

Ozaki J.; Nakagawa Y.; Sakurai G.; Tamai S.; Okumura M., 1990: Teflon felt cuff plasty for global or massive tears of the rotator cuff of the shoulder. Heimke, G , U Soltesz And A J C Lee (Ed ) Advances in Biomaterials, Vol 9 Clinical Implant Materials; Eighth European Conference on Biomaterials, Heidelberg, West Germany, September 7-9, 1989 Xvi+676p Elsevier Science Publishers B V : Amsterdam, Netherlands; New York, New York, Usa Illus 467-472

Andersen, A.; Haahr, V1; Jensen, E.1; Sandfaer, J., 1983: Effect of N nitrogen-fertiliser on yield, protein content, and symbiotic N-fixation in Pisum sativum L. grown in pure stand and mixtures with barley. World crops: production utilization description(8): 205-218

Washington, A.Eugene.; Coye, M.J.; Boulware, L.Ebony., 2016: Academic Health Systems' Third Curve: Population Health Improvement. JAMA 315(5): 459-460

Bartley, J.K.; Pope, M.; Knoll, A.H.; Semikhatov, M.A.; Petrov, P.Y., 1998: A Vendian-Cambrian boundary succession from the northwestern margin of the Siberian Platform: stratigraphy, palaeontology, chemostratigraphy and correlation. Geological Magazine y; 135(4): 473-494

Jin, Xiao-Hua, 2005: Coelogyne weixiensis (Orchidaceae), a new species from Yunnan, China. Coelogyne weixiensis X.H. Jin sp. nova (Orchidaceae) is described and illustrated. It is morphologically reminiscent of C. gongshanensis, from which it differs in having aristate lateral sepals, petals much narrower than the sepals, and toothed la...