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Effects of beta receptor blockade on left ventricular function in patients with cad a comparative study of acebutolol and esmolol


, : Effects of beta receptor blockade on left ventricular function in patients with cad a comparative study of acebutolol and esmolol. Der Anaesthesist 39(5): 264-268

Patients undergoing coronary artery bypass grafting are at risk for perioperative myocardial ischemia. Most such ischemic episodes occur without obvious hemodynamic changes. Tachycardia as a predictor for increased myocardial oxygen consumption doubles the incidence of myocardial ischemia when heart rate increases to over 110 beats/min. During the operative procedure for coronary revascularization, some maneuvers, e.g. intubation, sternotomy and mediastinal preparation, may be associated with tachycardia and increases in blood pressure despite an adequate level of anesthesia, so that the administration of .beta.-receptor blocking agents seem to be indicated.

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