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Factor H polymorphism, typing by isoelectrofocusing and immunoblotting: no association with rheumatoid arthritis

, : Factor H polymorphism, typing by isoelectrofocusing and immunoblotting: no association with rheumatoid arthritis. Human Heredity 40(1): 55-57

The genetic polymorphism of human factor H (.beta.1H) was investigated by a combination of isoelectrofocusing and immunoblotting. This simple method is reliable and economical. The allelic frequencies in the Newfoundland population were estimated to be 0.597 and 0.403 for FH*1 and FH*2, respectively (129 individuals typed). No association of factor H types with rheumatoid arthritis was found (111 patients typed).


PMID: 2138120

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