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Fibrinolytic inhibitors from the experimental rat epithelioma

, : Fibrinolytic inhibitors from the experimental rat epithelioma. Thrombosis Research 54(5): 457-466

Guerin epithelioma, a highly metastatic tumour implanted to Wistar rats contains two inhibitors of fibrinolysis which can be detected with the use of zymographic techniques. The first one - with Mr about 48000 forms SDS-stable complex with urokinase. The second - with Mr about 7000 inhibits fibrinolytic and amidolytic activity of plasmin.


PMID: 2528218

DOI: 10.1016/0049-3848(89)90215-6

Other references

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Colnot, S.; Fortes, P., 2014: Editing liver tumours. Gut 63(5): 709-710

Sykes, A.R.; Griffiths, R.G.; Slee, J., 1976: Influence of breed birth weight and weather on the body temperature of new born lambs. The rectal temperature of 208 lambs of Scottish Blackface, Tasmanian Merino, Southdown, Cheviot, Soay and Finnish Landrace breeds was measured between 15-25 min after birth, and that of 94 lambs again 1 h after birth. Relationships within breeds b...

Ransohoff, D.F.; Riddell, R.H.; Levin, B., 1985: Ulcerative colitis and colonic cancer. Problems in assessing the diagnostic usefulness of mucosal dysplasia. To assess the association of mucosal dysplasia and colonic cancer in patients with ulcerative colitis and to avoid bias in biopsy interpretation that may have affected results of previous studies, the authors examined coded histology slides from c...

Ohno, K., 2017: Studies on therapeutic strategies for congenital myasthenic syndromes. Congenital myasthenic syndromes(CMS)are caused by germline mutations in genes encoding molecules expressed at the neuromuscular junction. Mutations have been identified in 25 genes. Clinical phenotypes and rational therapies widely vary depending...

Marchi, M.M.; Longhi Wagner, H.M., 1995: Three new species of Bothriochloa Kuntze (Poaceae, Andropogoneae) from Brazil. B. eurylemma, B. meridionalis and B. velutina, discovered in Mato Grosso do Sul, Rio Grande do Sul and Parana, respectively, are described and illustrated.

Tomlinson, J.L.; Johnson, J.C., 2000: Quantification of measurement of femoral head coverage and Norberg angle within and among four breeds of dogs. Values for percentage coverage of the femoral head (PC) and Norberg angle (NA) in 24 to 48 month-old Labrador Retrievers (n=455), Golden Retrievers (n=423), Rottweilers (n=545) or German Sheperd (n=418) were reported, and values for each that dist...

Tunçbilek, M.; Kiper, Tğ.; Altanlar, N., 2008: Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA. The novel benzimidazole derivatives (3, 5, 8, 9, 12-14, 18-41) were prepared in this paper and the antimicrobial activities of these compounds against Staphylococcus aureus, methicillin-resistant S. aureus (MRSA, standard and clinical isolates), B...