Fibrinolytic inhibitors from the experimental rat epithelioma
Mirowski M.; Wierzbicki R., 1989: Fibrinolytic inhibitors from the experimental rat epithelioma. Thrombosis Research 54(5): 457-466
Guerin epithelioma, a highly metastatic tumour implanted to Wistar rats contains two inhibitors of fibrinolysis which can be detected with the use of zymographic techniques. The first one - with Mr about 48000 forms SDS-stable complex with urokinase. The second - with Mr about 7000 inhibits fibrinolytic and amidolytic activity of plasmin.