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Glutamate uptake in mammalian retinal glia is voltage dependent and potassium dependent

, : Glutamate uptake in mammalian retinal glia is voltage dependent and potassium dependent. Brain Research 516(2): 322-325

Glutamate evokes an inward membrane current in glial cells form the rabbit retina, by activating high-affinity glutamate uptake. Uptake is strongly inhibited by depolarization. It is also inhibited by removing extracellular sodium or intracellular potassium and by raising the extracellular potassium concentraiton, suggesting that the uptake carrier transports sodium ions into and potassium ions out of the cell. The voltage- and potassium-dependence of glutamate uptake may have clinical implications: during anoxia, when [K+]0 rises, uptake will be inhibited and the extracellular glutamate concentration may then rise to neurotoxic levels.


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Kvas, A.; Seljak, J., 2015: Unreported workplace violence in nursing. Workplace violence occurs on a frequent basis in nursing. Most violent acts remain unreported. Consequently, we do not know the actual frequency of the occurrence of workplace violence. This requires research of nurses' actions following work...

Leeds N.E.; Rosenblatt R.; Zimmerman H.M., 1971: Focal angiographic changes of cerebral lymphoma with pathologic correlation a report of 2 cases. Radiology 99(3): 595-599

Suzuki, K.-Yamashita; Yamanouchi, K., 1998: Inhibitory pathway for female sexual behavior in male rat brain: Effect of medial forebrain bundle (MFB) cuts. In order to clarify the role of the medial forebrain bundle (MFB) in regulating female sexual behavior in male rats, lordosis and soliciting behavior were observed after transection of it. Male rats were castrated and received cutting of the bilat...

Fleig, R., 1990: Gastrulation in the zebrafish Brachydanio rerio (Teleostei) as seen in the scanning electron microscope. NATO ASI (Advanced Science Institutes) Series Series A Life Sciences, 195: 329-338

Maeda Y.; Yamamoto M.; Masui T.; Sugiyama K.; Yokota M.; Okada N.; Sugiyama K.; Katayama H.; Nakagomi K., 1991: Hyaluronidase inhibitor in the fruit of citrus reticulata blanco. Fifty percent of ethanolic extracts from the immature fruits of Citrus reticulata BLANCO, C. tamurana hort. ex TANAKA, C. natsudaidai HAYATA and C. unshiu MARKOVICH showed a significant inhibitory effect on the activation of inactive hyaluronidase...

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Post, H.D., 1888: The Influence of Forests upon Rainfall and Climate. Science 11(260): 50-50

Weel, P.B. van., 1953: Mechanical properties of the resting holothurian muscle. Proceedings Hawaiian Academy of Science, 28: 6-7

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Lang, A.B.; Schürch, U.; Zimmermann, F.; Bruderer, U., 1992: Selective generation of antigen-specific human hybridomas optimized for large scale growth in serum-free medium. The direct propagation of newly formed human hybridomas in serum-free medium selects for hybrids with a metabolism best suited to growth in this environment. Under optimal culture conditions, this procedure results in the generation of antigen-spe...