geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Habituation and sensitization of plasma catecholamine responses to chronic intermittent stress effects of stressor intensity


, : Habituation and sensitization of plasma catecholamine responses to chronic intermittent stress effects of stressor intensity. Physiology & Behavior 47(4): 647-652

Adult male Sprague-Dawley rats were exposed acutely (1 time for 30 minutes) or chronically (30 minutes per day for 27 days) to swim stress in water maintained at either 18.degree. C, 24.degree. C or 34.degree. C. Each rat was prepared with an indwelling tail artery catheter to allow for direct measures of mean arterial pressure (MAP, mmHg) and heart rate (HR, beats per minute) and for remote collection of blood samples before, during and after the 1st or 27th swim stress session. Blood samples were later analyzed for plasma levels of norepinephrine and epinephrine to serve as an assessment of sympathetic-adrenal medullary activity. Compared to handled controls, body weight gain was reduced significantly in rats exposed chronically to swim stress at any of the 3 temperatures. However, baseline values of MAP and HR and plasma levels of norepinephrine and epinephrine were similar in chronically stressed rats compared to their handled controls. The plasma norepinephrine response of rats exposed chronically to either 18.degree. C or 24.degree. C swim stress was significantly greater than that of matched controls stressed for the first time. In contrast, the plasma epinephrine response of chronically stressed rats from these two groups was slightly but not significantly reduced compared to matched controls. For swim stress at 34.degree. C, the plasma norepinephrine and epinephrine responses of chronically stressed rats was stressed rats were reduced significantly compared to controls stressed for the first time. These findings demonstrate that stressor intensity affects sensitization and habituation of plasma catecholamine responses in laboratory rats exposed to chronic intermittent stress. In addition, the results of these experiments suggest that the sympathetic nervous system and the adrenal medulla respond differentially to manipulations of stressor intensity.

US$19.90

PMID: 2385634

DOI: 10.1016/0031-9384(90)90072-c


Other references

Da-Ros, C.-Orlando; Aita, C.; Giacomini, S.-Jose, 2005: Volatilizacao de amonia com aplicacao de ureia na superficie do solo, no sistema plantio direto. The experiment was carried out in 2002/03, at the Federal University of Santa Maria, State of Rio Grande do Sul, Brasil, in a typic Haoludal under six years of no-tillage to evaluate the effects of black oat residues left at soil surface on ammoni...

Grindrod S.; Round J.M.; Rutherford O.M., 1987: Type 2 fiber composition and force per cross sectional area in the human quadriceps. Journal of Physiology (Cambridge) 390: 154P

Alvarez, A.; Rodger, J.; Brosio, C.; Cinat, G.; Giglio, R.; Carnaval, S.; Cresta Morgado, C.; Noblia, C.; Delfino, C.; Mickiewicz, E., 2002: Neoadjuvant chemotherapy for stage III breast cancer Does the addition of paclitaxel to doxorubicin increase complete response A single institution non randomized study. European Journal of Cancer 38(Supplement 3): S73, March

Valkov, I., 1975: The fine structure of the lymphocyte nucleus under conditions of phytohaemagglutinin stimulation. The nucleus of PHA (phytohaemagglutinin) cultured lymphocytes is studied by EDTA, Thalium-Schiff and uranyl-lead techniques. Scattering of the dense chromatin, increase in the number of NB (nuclear bodies) and nucleolar modifications are establish...

Motoi, T.; Ishida, T.; Kawato, A.; Motoi, N.; Fukayama, M., 2005: Pigmented neurofibroma: review of Japanese patients with an analysis of melanogenesis demonstrating coexpression of c-met protooncogene and microphthalmia-associated transcription factor. Pigmented neurofibroma (PNF) is a rare variant of neurofibroma showing melanin production. To clarify the clinicopathologic features of PNF and to characterize melanogenesis in PNF, 12 cases; of PNF were examined in comparison with schwannoma (SCH...

Zhang, L.Ying.; Zhang, W.; Zhou, Z.; Li, C.Ming., 2016: γ-Fe2O3 nanocrystals-anchored macro/meso-porous graphene as a highly efficient adsorbent toward removal of methylene blue. An adsorbent, γ-Fe2O3 nanocrystals-anchored macro/meso-porous graphene was synthesized by metal etching approach toward removal of methylene blue, exhibiting rapid adsorption rate, high adsorption capacity and good recyclability, thus holding a g...

Dijkhuizen, A.A., 1986: PorkCHOP: an economic microcomputer replacement model for sows. A computer model called PorkCHOP, was developed in an electronic spreadsheet on the microcomputer to help farmers, veterinarians and other livestock specialists reach economically sound culling decisions in swine breeding herds. It quantifies the...

Sule, J.D.; Skoog, S.J.; Tank, E.S., 1994: Perineal lipoma and the accessory labioscrotal fold: an etiological relationship. Congenital scrotal disorders are unusual, including penoscrotal transposition, bifid scrotum, ectopic scrotum and accessory scrotum. The latter 2 entities are extremely rare. Because accessory scrota usually arise in the absence of associated anom...

Paulun, V.C.; Kawabe, T.; Nishida, S'ya.; Fleming, R.W., 2016: Seeing liquids from static snapshots. Perceiving material properties can be crucial for many tasks-such as determining food edibility, or avoiding getting splashed-yet the visual perception of materials remains poorly understood. Most previous research has focussed on optical characte...

Nii, H.F.rukawa, K.I.akiri, M.K.bota, T., 1979: Transformation of litsenolide A1, A2, B1 and B2 under saponification. Agricultural and biological chemistry 43(6): 1349-1350