+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Hiv antibodies in pediatric hemophiliacs in nagasaki japan

, : Hiv antibodies in pediatric hemophiliacs in nagasaki japan. Acta Medica Nagasakiensia 34(1): 47-52

Human immunodeficiency virus (HIV) antibodies were assayed in 34 pediatric patients (28 patients with hemophilia A, 3 hemophilia B, and 3 von Willebrand's disease) of Nagasaki Prefecture. Thirteen of hemophilia A patients were positive (46.4%), 2 of hemophilia B patients were positive (66.7%) and 1 of von Willebrand's disease patients was positive (33.3%). Seropositive patients totaled 16 out of 34 and sero-positive rate was 47.1%. In Nagasaki University Hospital, HIV-antibodies were detected in 6 of 9 hemophilia A patients, but none in hemophilia and von Willebrand's disease patients. When compared with sero-negative patients, sero-positive patients had a depressed helper/suppressor T (OKT4/T8) ratio and a relative increase in serum IgG levels (p < 0.05). Absolute lymphocyte counts in sero-positive patients did not differ from sero-negative patients. The reverse transcriptase activities were detected in the peripheral mononuclear cell cultures in 3 of 4 sero-positive hemophilia A patients from Nagasaki University Hospital by Dri J. A. Levy in 1985. The above results suggest that exposure to HIV is widespread in asymptomatic hemophiliacs. Hence, further studies for preventive measures and therapy of Acquired Immunodeficiency Syndrome (AIDS) must be implemented.


Other references

Egoshin, I.S.; Peregudov, T.A.; Pol' nikov, D.G., 1975: Dynamics of morphological changes (in guinea-pigs) following intramuscular injection of Clostridium oedematiens toxin. Guinea-pigs given i/m injections of 1.5 ml of toxin of the virulent strain 34 of Cl. oedematiens died after 15-18 hours. Groups of three animals were killed 1, 2, 3, 6, 9, 12 and 15 hours after injection. Lesions were found in all internal organs...

Rodova, RA., 1974: The chironomid females (Diptera, Chironomidae). 11. Chironomus pilicornis Fabr. Informatsionnyi Byull Biol Vnutr Vod, 21: 44-47

Piccoli, S.P.; Caimi, P.G.; Cole, M.D., 1984: A conserved sequence at c-myc oncogene chromosomal translocation breakpoints in plasmacytomas. Many recent studies have shown that chromosomal translocation breakpoints frequently occur near cellular proto-oncogenes (reviewed in ref. 1). In both mouse plasmacytomas and Burkitt lymphomas, the c-myc oncogene becomes joined to an immunoglobuli...

Lengerova, A., 1955: Method of investigation of the effect of ionizing radiations on microorganisms. Ceskoslovenska Biologie 4(1): 45-52

Bettero, A.B.nassi, C., 1983: Determination of bergapten and citropten in perfumes and suntan cosmetics by high-performance liquid chromatography and fluorescence. Journal of chromatography 280(1): 167-171

Voets, R.; Lagrou, A.; Hilderson, H.; Van Dessel, G.; Dierick, W., 1979: RNA synthesis in isolated bovine thyroid nuclei and nucleoli. alpha-Amanitin effect, a hint to the existence of a specific regulatory system. DNA dependent RNA polymerase activities in isolated bovine thyroid nuclei and nucleoli have been studied. They retain their RNA synthetic activity for an extended period of time. This RNA synthetic activity is sensitive to actinomycin D and requir...

Choi, Y.; Park, J.; Ko, Y.San.; Kim, Y.; Pyo, J-Soo.; Jang, B.Gun.; Kim, M.A.; Lee, J-Seon.; Chang, M.Soo.; Lee, B.Lan., 2017: FOXO1 reduces tumorsphere formation capacity and has crosstalk with LGR5 signaling in gastric cancer cells. Gastric cancer (GC) is a major of cause of cancer-related death and is characterized by its heterogeneity and molecular complexity. FOXO1 is a transcription factor that plays a key role in GC growth and metastasis. However, the implication of FOXO...

Kaushik, V.V.; Lynch, M.P.; Dawson, J.K., 2002: Tc-DTPA clearance and rheumatoid arthritis-associated fibrosing alveolitis. Rheumatology 41(6): 712; Author Reply 712-3

Terashima, M.; Meyer, C.H.; Keeffe, B.G.; Putz, E.J.; de la Pena-Almaguer, E.; Yang, P.C.; Hu, B.S.; Nishimura, D.G.; McConnell, M.V., 2005: Noninvasive assessment of coronary vasodilation using magnetic resonance angiography. OBJECTIVES The purpose of this study was to investigate the use of coronary magnetic resonance angiography (MRA) for assessing human epicardial coronary artery vasodilation. BACKGROUND Coronary vasodilation plays a vital role in the human coronary...

Dicker, S.E., 1953: A method for the assay of very small amounts of antidiuretic activity with a note on the antidiuretic titre of rat's blood. In rats under ethanol anesthesia and kept with a constant water load, the smallest dose of vaso-pressin injected intraven. which had an antidiuretic effect was 3.5 [mu] U/100 g. body wt. The largest dose having a differential effect was 50[mu] U/1...