geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical detection of c5b 9 complement complex in early stages of myocardial necrosis in paraffin sections


, : Immunohistochemical detection of c5b 9 complement complex in early stages of myocardial necrosis in paraffin sections. Zeitschrift fuer Rechtsmedizin 103(3): 199-206

With conventional staining techniques it was nearly impossible to differentiate with certainty between early ischemic myocardial lesions, autolytic changes and intact myocardium without a nuclear section. In 1986 it was introduced an immunohistochemical method, which presented C5b-9 Complement Complex as a necrosis marker in cryostat sections. Our further development of this process has resulted in a technique for application on routine paraffin sections: C5b-9 Complement Complex is particularly well-suited for the exact and autolytically insensitive presentation of disseminated necroses of fiber bundles and single fibers of myocardium. The application of the technique on paraffin sections will lead to the use of the same in forensic medicine routine diagnostics of early ischemic myocardial lesions, even in cases of "sudden" cardiac death.

US$29.90


Other references

Anonymous, 2013: Gonadal differentiation and puberty onset in the zebrafish Evidence for the dependence of puberty onset on body growth but not age in females. Puberty is the period in the vertebrate life cycle that marks the transition from sexual immaturity to maturity, enabling an animal to acquire adult reproductive functions. An important point in vertebrate reproductive life, puberty has been under...

Kimak, A.; Kern, Z.; Leuenberger, M., 2015: Qualitative Distinction of Autotrophic and Heterotrophic Processes at the Leaf Level by Means of Triple Stable Isotope (C-O-H) Patterns. Foliar samples were harvested from two oaks, a beech, and a yew at the same site in order to trace the development of the leaves over an entire vegetation season. Cellulose yield and stable isotopic compositions (δ(13)C, δ(18)O, and δD) were an...

Lampl, C.; Katsarava, Z.; Diener, H-C.; Limmroth, V., 2005: Lamotrigine reduces migraine aura and migraine attacks in patients with migraine with aura. This study examined the efficacy of lamotrigine in the prevention of migraine aura. Fifty nine patients suffering from migraine with aura received lamotrigine in a controlled three year prospective open study. Treatment response was defined as a r...

Landa L.; Chevez A.; Martinez P.A.; Resano F., 1981: Dynamic morphology of the adult human liver cells cultivated in vitro. Gastroenterology 80(5 PART 2): 1338

Thomas, M.C.; Jennett-Reznek, A.M.; Patanwala, A.E., 2012: Combination of ketamine and propofol versus either agent alone for procedural sedation in the emergency department. The safety of using ketamine-propofol combinations as an alternative to using either agent alone for procedural sedation is discussed. A total of 10 trials comparing the combination of ketamine and propofol with either agent alone for procedural s...

Ohtsuka, Y.; Shimada, T.; Watanabe, N.; Akiyama, H.; Suzuki, Y.; Ishida, M.; Hiraishi, H.; Terano, A., 1997: Analysis of the vacA gene sequences among Helicobacter pylori strains isolated from Japanese patients. Gastroenterology 112(4 SUPPL ): A243

Zhu, W.J.; Roper, S.N., 2000: Reduced inhibition in an animal model of cortical dysplasia. Cortical dysplasia has a strong association with epilepsy in humans, but the underlying mechanisms for this are poorly understood. In utero irradiation of rats produces diffuse cortical dysplasia and neuronal heterotopia in the neocortex and hippo...

Ohadi, K.; Aghamohseni, H.; Legge, R.L.; Budman, H.M., 2015: Fluorescence-based soft sensor for at situ monitoring of Chinese hamster ovary cell cultures. Multi-wavelength fluorescence spectroscopy was investigated as a potential tool for use in monitoring key process variables that include: viable and dead cells, recombinant protein, glucose, and ammonia concentrations for Chinese hamster ovary (CH...

Deng, Z.; Cai, L.; Jin, W.; Ping, A.; Wei, R., 2014: One-stage reconstruction with open bone grafting and vacuum-assisted closure for infected tibial non-union. Non-union of the tibia complicated by osteomyelitis is one of the most challenging problems in orthopaedic surgery. There remains a significant amount of debate and controversy regarding the optimal medical management of infected tibial non-union....

Wright, C., L.; Boulant, J., A., 2007: Carbon dioxide and pH effects on temperature-sensitive and -insensitive hypothalamic neurons. The preoptic-anterior hypothalamus (POAH) controls body temperature, and thermoregulatory responses are impaired during hypercapnia. If increased CO2 or its accompanying acidosis inhibits warm-sensitive POAH neurons, this could provide an explana...