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On the role of neurochemical mechanisms of the dorsal raphe nucleus in different alarm state model in rats

, : On the role of neurochemical mechanisms of the dorsal raphe nucleus in different alarm state model in rats. Zhurnal Vysshei Nervnoi Deyatel'nosti Imeni I P Pavlova 39(6): 1124-1128

Dopamine and serotonin microinjection in the dorsal raphe nucleus of rats does not influence the alarm state in the test of "threatening situation" avoidance, but increases or weakens the state of alarm in the rest of "illuminated site" avoidance. Local injection of GABA in this midbrain formation weakens the alarm state in the test of "threatning situation" avoidance but is not effective in the test of "illuminated site" avoidance. Chemical stimulation of the raphenucleus by glutaminic acid does not influence the two different experimentally modelled states of alarm, but modulates the mechanisms controlling the instinct of darkness preference by rats.


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