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Presence and localization of proteins immunologically related to erythrocyte protein 4.1 in human skin

, : Presence and localization of proteins immunologically related to erythrocyte protein 4.1 in human skin. Histochemistry 95(6): 549-554

Analogues of human erythrocyte protein 4.1 have been examined in the human skin by immunochemical techniques using anti-human erythrocyte protein 4.1 antibodies. Immunoblot analysis revealed that human epidermis contains 4.1-like proteins of 80 kDa and 78 kDa that cross react with anti-protein 4.1 antibodies. Analysis with immunofluorescence microscopy revealed that the plasma membrane of the human epidermal keratinocyte was stained intensively in the basal cells, whereas spinous cells were moderately stained. It is noted that eccrine sweat gland cells and ductal cells were also stained in the peripheral cytoplasma. Taken together, these results demonstrate that 4.1-like proteins are present in human epidermal keratinocytes, eccrine sweat gland cells and ductal cells. The present findings enable us to suggest that a membrane skeletal protein lattice might exist in these cells.


PMID: 1856108

DOI: 10.1007/bf00266740

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Blais, C.; Sefiani, M.; Toullec,; Soyez, D., 1994: In vitro production of ecdysteroids by Y-organs of Penaeus vannamei Correlation with hemolymph titers. Ecdysteroids secreted in vitro by Y-organs of the white shrimp Penaeus vannamei were quantified at different stages of the molt cycle by enzyme immunoassay (EIA). The production was maximal during the first hour of incubation and the highest value...

Anon, 1982: Virology for the food program. Voprosy Virusologii (6): 649-651

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Stepanov, E.A.; Vodolazov, I.A., 1963: Congenital Lobar Pulmonary Emphysema. Khirurgiia 39: 31-37

Viggiani, G.; Nieves-Aldrey, JL., 1993: Prima segnalazione di Goetheana shakespearei Girault (Hymenoptera Eulophidae), parassitoide esotico di Thysanoptera, per l'Europa. Goetheana shakespearei Girault (Hymenoptera Eulophidae), exotic parasitoid of Thysanoptera, has been recorded for the first time from Europe (Spain). Notes on the systematic position of the eulophid, the main morphological characteristics for the...

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Suzuki, M.; Uchida, K.; Morozumi, M.; Hasegawa, T.; Yanai, T.; Nakayama, H.; Tateyama, S., 2003: A comparative pathological study on canine necrotizing meningoencephalitis and granulomatous meningoencephalomyelitis. Canine necrotizing meningoencephalitis (NME) and granulomatous meningoencephalomyelitis (GME) were compared pathologically. Gross observation exhibited lateral ventricular dilation and discoloration, malacia and/or cavitation of the cerebrum in NM...

Hodge F.A.; Nachtwey D.S., 1971: X ray induced delay of cell division in synchronized tetrahymena a time and dose dependent transition to in sensitivity. Radiation Research 47(1): 287

Rao, KR.; Fingerman, M.; Hays, C., 1972: Comparison of the abilities of a - ecdysone and 20- hydroxyecdysone to induce precocious proecdysis and ecdysis in the fiddler crab Uca pugilator. Zeitschrift vergl Physiol, 763: 270-284