+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Reactivity and action mechanism of triazenes vi. triazenes and diazo compounds as modulators of replicative and repair dna synthesis

, : Reactivity and action mechanism of triazenes vi. triazenes and diazo compounds as modulators of replicative and repair dna synthesis. Khimiko Farmatsevticheskii Zhurnal 23(4): 396-398

To study new aspects of the mechanism of antitumor action displayed by triazenes, a number of diazo- and triazenoderivatives were synthesized and tested in vitro for effects on DNA replicative and repair synthesis of human lymphocytes. Triazenes were shown to possess a direct modulatory (inhibitory or stimulant) action on the biochemical processes under study.


Other references

Zito, F.; Savi, A.; Fazio, F., 1993: CERASPECT: A brain-dedicated SPECT system: Performance evaluation and comparison with the rotating gamma camera. Physical parameters and performance of a new brain-dedicated tomograph (CERASPECT) were measured and compared to those of a state-of-the-art single-headed rectangular rotating gamma camera. Spatial resolution, sensitivity, scatter fraction, contra...

Lodge, M.P., 1976: The structuring of knowledge in graduate education curricula. Nln Publications: 21-32

Vasileva, M., 1962: Raising hard seed germination in certain species of Vicia genus.. In experiments with 8 species of Vicia the best method for increasing germination was scarification. Sulphuric-acid treatment for 15 min also increased germination and, for V. pannonica, V. villosa and V. varia, which had smaller percentages of ha...

Anonymous, 1996: Crustal movements in the southeastern Kyushu District; November, 1993-October, 1995. Jishin Yochi Renrakukai Kaiho = Report of the Coordinating Committee for Earthquake Prediction 55: 637-643

Hawthorne S.B.; Miller D.J., 1987: Comparison of supercritical fluid solvents for the extraction and recovery of pah from environmental solids. Abstracts of Papers American Chemical Society 193

Mayorek, N.; Naftali-Shani, N.; Grunewald, M., 2011: Diclofenac inhibits tumor growth in a murine model of pancreatic cancer by modulation of VEGF levels and arginase activity. Diclofenac is one of the oldest anti-inflammatory drugs in use. In addition to its inhibition of cyclooxygenases (COX), diclofenac potently inhibits phospholipase A(2) (PLA(2)), thus yielding a broad anti-inflammatory effect. Since inflammation is...

Ayerza, R.; Coates, W., 1996: New industrial crops: Northwestern Argentina Regional Project. The Northwestern Argentina Regional Project was initiated in 1991 to identify new industrial crops and bring them into commercial production in order to help diversify agricultural production and increase profits for farmers in northwestern Argent...

Han Shu Hong; Chen Yun Tao;; Zhu Xiao Hui; Zhang Ling; Zhang Yan; Gao Xiao Ming, 2003: Biological functional analysis of autoreactive T cells from BXSB mice. Objective: Analyzing biological function of ATL, an autoreactive T cell line from lupus-prone mice BXSB to study the feasibility of TCV (T cell vaccine) in the SLE. Method: Detecting the proliferation of ATL with 3H-TdR incorporation and the level...

Thyagaraja, B.S.; Sarkar, H.B., 1970: Compensatory hypertrophy of the contralateral testis after unilateral castration in the toad, Bufo melanostictus (Schn). Experientia 26(5): 544-545

Jelinkova A.; Benda R.; Danes L., 1971: Electron microscopy study of development of poxvirus officinale infection in alveolar macrophages in vitro. Folia Microbiologica 16(6): 540