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The clinical investigation of the combined treatment of interferon and chinese drugs on patients with chronic active hepatitis b


, : The clinical investigation of the combined treatment of interferon and chinese drugs on patients with chronic active hepatitis b. Virologica Sinica 6(2): 113-116

In the present study, we report the therapeutic evaluation of 181 patients with chronic active hepatitis (CAH), who were treated with interferon and Chinese drugs (Group I), interferon (Group II), heat-clearing and detoxifying Chinse drugs (Group III), Chinese and western drugs (Group IV). Recuperative rate of liver function after treatment was 78.5%, 73.6%, 54.5%, 40.4% respectively. Negative conversion rate of HBeAg was 66.6%, 73.3%, 15.4%, 21.8% respectively. The results show that Group I and II are eutherapeutic; among them, the therapueutic effectiveness of Group I is significantly better than that of Group III, IV (p < 0.05, p < 0.01), the curative effect of Group II is better than that of Group IV (p < 0.05). It is suggested that the combined treatment of interferon and Chinese drugs to patients with CAH be more eutherapeutic, compared with Chinese drugs or interferon only.

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