geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The effect of chemical radiation protectors on cell cycle progression after gamma or neutron irradiation


, : The effect of chemical radiation protectors on cell cycle progression after gamma or neutron irradiation. Cell Proliferation 24(3): 271-280

The effects of two chemical radiation protectors, WR-1065 and WR-151326, were characterized in V79 Chinese hamster cells after cobalt-60 (60Co) gamma or fission spectrum neutron irradiation. Each protector was administered at a concentration of 4 mM to exponentially growing cultures for 30 min prior to and during irradiation with either 60Co gamma or JANUS fission spectrum neutrons. After irradiation the cells were either plated immediately for survival or returned to the incubator and assayed for cell progression. Aliquots of cells were removed at selected times, counted, fixed and stained with 4'6-diamidino-2-phenylindole (DAPI). Analysis of DNA histograms indicate that the presence of the protector during irradiation reduced the division delay experienced at the G2-M interface. Implications of these effects are discussed.

US$19.90

PMID: 2039803

DOI: 10.1111/j.1365-2184.1991.tb01156.x


Other references

Mikamo H.; Sawairi M.; Itoh N.; Itoh K.; Tamaya T.; Watanabe K.; Ueno K., 1991: The bacterial flora in patients with endometrial cancer. International Journal of Gynecology & Obstetrics (ABSTR SUPPL): 280

Senatore, G.; Saviolo, R.; Centofanti, P.; D.S.mma, M.; Fazzari, M., 2000: Relation between power and temperature during intraoperative radiofrequency catheter ablation Implications for larger electrodes use. European Heart Journal 21(Abstract Supplement): 446, August-September

Van Den Heuvel, J.E., 1962: Treatment of choroiditis disseminata acuta by prednison. Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift für Augenheilkunde 144: 291-294

Lapeyssonnie, L., 1971: Cholera: why?. Medecine Tropicale 31(1): 9-16

Heidemann H.; Gerkens J.; Branch R.; Spickard A., 1982: Salt loading inhibits amphotericin b ampho nephro toxicity. Clinical Pharmacology & Therapeutics 31(2): 234

Dietzel, G.T.W., 2004: German Federal Ministry for Health and Social Security. Studies in Health Technology and Informatics 96: 5-6

Leboeuf, M.; Cavé, A.; Conreur, C.; Lusinchi, X.; Goutarel, R., 1969: Steroid alkaloids. LXXXIV. (25). Synthesis of 18-hydroxyprogesterone and 18-nor-13 beta hydroxyprogesterone from conessine. Annales Pharmaceutiques Francaises 27(4): 289-302

Dedenko I.K.; Zakharash M.P.; Nikolaev V.G., 1983: Hemo sorption in the combined treatment of rheumatoid arthritis. Revmatologiya (4): 10-12

Dandrifosse, G.; Schoffeniels, E., 1964: Action de quelques oses sur la secretion de chitinase par la muqueuse gastrique isolee. Archives Internationales de Physiologie et de Biochimie, 72: 517-519

Kyle, F.E.; Harris, M., 2006: Concurrent correlates and predictors of reading and spelling achievement in deaf and hearing school children. Seven- and eight-year-old deaf children and hearing children of equivalent reading age were presented with a number of tasks designed to assess reading, spelling, productive vocabulary, speechreading, phonological awareness, short-term memory, and...