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Acute social stress and cardiac electrical activity in rats

, : Acute social stress and cardiac electrical activity in rats. Aggressive Behavior. 24(4): 287-296

This paper summarizes the results of experiments aimed at describing electrocardiographic responses to different acute social stressors in healthy male rats. Electrocardiograms were telemetrically recorded during maternal aggression, social defeat, and psychosocial stimulation, as obtained using the classical resident-intruder paradigm. Autonomic input to the heart was indirectly evaluated by means of heart rate variability measures and plasma catecholamine level determinations. Social stressors produced changes in cardiac electrical activity that were markedly higher than those observed in nonsocial challenging conditions such as novelty and restraint. Defeat, which produced the highest catecholaminergic responses, was the most potent as a social aversive experience in inducing heart rate accelerations and arrhythmias, particularly when applied to a wild-type strain of rats. The far most frequent arrhythmic events were ventricular and supraventricular premature beats, either as isolated events or grouped. Ventricular premature beats usually occurred immediately after attacks and in association with higher heart rate values and lower heart rate variability scores. The relationships between the type of stressor used (either social or nonsocial), the different contributions of the emotional and physical components of stress response, the resulting modulation of autonomic control over cardiac electrical activity, and the incidence of arrhythmic events are discussed.


DOI: 10.1002/(sici)1098-2337(1998)24:4<287::aid-ab4>;2-g

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Häusler, M.; Sellhaus, B.; Scheithauer, S.; Engler, M.; Alberg, E.; Teubner, A.; Ritter, K.; Kleines, M., 2005: Murine gammaherpesvirus-68 infection of mice: A new model for human cerebral Epstein-Barr virus infection. Epstein-Barr virus infection may cause severe neurological complications that are not mirrored by animal models. Here, we show that nasal inoculation of newborn BALB/c wild-type mice with MHV-68, a murine gammaherpesvirus, causes cerebral infectio...

Cuilleret, J.; Regairaz, C.; Tram, T.P., 1982: Immediate and long-term results of cryosurgical haemorrhoidectomy. A retrospective study of 240 cases of haemorrhoids treated by cryosurgery with a 1 to 5 years' follow-up confirmed the immediate and long-term effectiveness of this method which resulted in lasting cure in more than 95% of the cases. The main...

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Boshell, B.R.; Sanford, J.P., 1958: A screening method for the evaluation of urinary tract infections in female patients without catheterization. Clean-voided specimens have long been used for cultures from male patients, but catheterization has usually been necessary to obtain adequate cultures from the female. The catheter has been implicated as a possible source of infection; therefore,...

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