+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Bacterial translocation: the influence of dietary variables

, : Bacterial translocation: the influence of dietary variables. Gut 35(1 Suppl): S23-S27

Transmucosal passage of bacteria in critically ill patients may lead to a significant incidence of systemic sepsis. This has attracted much clinical interest, as it has been shown that malnutrition in itself, impairs various aspects of barrier function. Bacterial translocation is increased in animal models where nutrients are given by the parenteral route, while enteral feeding reverses this. Translocation is also considerably increased in response to a non-lethal endotoxin challenge, if there is pre-existing protein energy malnutrition. Similar results have been obtained where the insult is caused by the inflammatory agent, zymosan. Dietary fibre reduces the deleterious effects of either agent on translocation, although the type of fibre is important. Bulk forming but non-fermentable fibres are more effective than easily fermentable types (for example, pectin). Glutamine was not effective in preventing elemental diet induced bacterial translocation. Thus, although fermentable fibre and glutamine have positive effects on mucosal mass, they do not affect translocation. Enteral nutrition thus seems to be superior to parenteral nutrition in maintaining the functional barrier of the gut. A clearer understanding of the physiology of these effects may lead to use of specifically modified enteral diets in the critically ill patient.


PMID: 8125385

DOI: 10.1136/gut.35.1_Suppl.S23

Other references

Sharma, M.; Saxena, S.K., 1992: Effect of Meloidogyne incognita (root-knot nematode) and Aspergillus niger on growth and root-knot development on tomato. Germination of tomato seeds was adversely affected by culture filtrates of A. niger, however, germination improved with increasing dilution of the filtrate. When seedlings were inoculated with A. niger alone there was an improvement in growth. Com...

Sutton, S.; Bickler, G.; Sancho-Aldridge, J.; Saidi, G., 1994: Prospective study of predictors of attendance for breast screening in inner London. To investigate the predictors of first-round attendance for breast screening in an inner city area. Prospective design in which women were interviewed or completed a postal questionnaire before being sent their invitation for breast screening. Soc...

Anonymous, 2011: Effects of a Family Intervention in Reducing HIV Risk Behaviors Among High-Risk Hispanic Adolescents A Randomized Controlled Trial. To determine the efficacy of a family intervention in reducing human immunodeficiency virus (HIV) risk behaviors among Hispanic delinquent adolescents. Randomized controlled trial. Miami–Dade County Public School System and Miami–Dade...

Boies, A.M.; Roberts, J.T.; Girshick, S.L.; Zhang, B.; Nakamura, T.; Mochizuki, A., 2009: SiO2 coating of silver nanoparticles by photoinduced chemical vapor deposition. Gas-phase silver nanoparticles were coated with silicon dioxide (SiO2) by photoinduced chemical vapor deposition (photo-CVD). Silver nanoparticles, produced by inert gas condensation, and a SiO2 precursor, tetraethylorthosilicate (TEOS), were expo...

Kamata, K.; Sasaki, H.; Munehisa, N.; Yamashina, T.; Sato, T.; Tsuru, H., 1978: A case of bite raising based on function and sensation of patient. Hiroshima Daigaku Shigaku Zasshi. Journal of Hiroshima University Dental Society 10(2): 291-295

Taylor, T.L., 1975: Suture material: a comprehensive review of the literature. Journal of the American Podiatry Association 65(7): 649-661

Giannini, S.H.; D'Alesandro, P.A., 1984: Isolation of protective antigens from Trypanosoma lewisi by using trypanostatic (ablastic) immunoglobulin G from the surface coat. Antigens were purified from extracts of Trypanosoma lewisi on immunoadsorbent columns of trypanostatic immunoglobulin G eluted from parasite surface coats at 8 days postinfection. Eight absorbed proteins, with molecular weights between 15,000 and...

Nunez Andrade, R., 1963: Dermatozoonosis. The author gives the name of dermatozoonosis to cutaneous diseases due to the infestation or sensitization by animals or to their products. Among others, in Mexico the most frequently found are due to Pulex, Clmex, Pediculus, Culicidae, ticks, fli...

Anonymous, 1953: Viennese Physicians' Association; Scientific Session on May 9, 1952. Klinische Medizin; Osterreichische Zeitschrift für Wissenschaftliche und Praktische Medizin 8(1): 41-48

Searle E.J., 1944: Geology of the southern Waitakere hills region west of Auckland city. The region west of Auckland, New Zealand, is composed mainly of the volcanic Maukau breccias, underlain by the Waitemata series (Tertiary). The petrography and origin of the breccias and of included clastic dikes are considered.