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Clustering of cholesterol in DMPC bilayers as indicated by membrane mechanical properties

, : Clustering of cholesterol in DMPC bilayers as indicated by membrane mechanical properties. General Physiology and Biophysics 12(3): 283-291

Mechanical characteristics of bilayer lipid membranes (BLM) composed of dimyristoylphosphatidylcholine (DMPC) and cholesterol in the gel and liquid crystalline state were studied by measuring the modulus of elasticity in direction perpendicular to the BLM plane, E perpendicular. The value of E perpendicular varied nonmonotonically with the cholesterol concentration, with a maximum around c = 50 mol% cholesterol. E perpendicular of BLM in gel state was about 2 times higher than that measured for the liquid crystalline state but the shape of E perpendicular (c) curves was similar for both states of the membrane. This may be due to the formation of cholesterol clusters at c > 50 mol% in both phase states of BLM.


PMID: 8224784

Other references

Marion, P., 1981: Looking toward the future of surgery. Chirurgie; Memoires de L'academie de Chirurgie 107(9): 723-728

Kristensen, A.K.; Brunstedt, J.; Nielsen, J.E.; Mikkelsen, J.D.; Roepstorff, P.; Nielsen, K.K., 1999: Processing, disulfide pattern, and biological activity of a sugar beet defensin, AX2, expressed in Pichia pastoris. AX2 is a 46-amino-acid cysteine-rich peptide isolated from sugar beet leaves infected with the fungus Cercospora beticola (Sacc.). AX2 strongly inhibits the growth of C. beticola and other filamentous fungi, but has little or no effect against bac...

Eidmann, H.H.; Nuorteva, M., 1968: The effect of population density and other factors on the number of offspring of Myelophilus piniperda. A team study carried out simultaneously in Denmark, Finland, Norway and Sweden from 1961 to 1967 on Pine bolts in breeding cages. At population densities of up to ca. 200 females/sq.m. of surface, the number of galleries increased proportionately...

Sabroe, I.; Parker, L.C.; Wilson, A.G.; Whyte, M.K.B.; Dower, S.K., 2002: Toll-like receptors: Their role in allergy and non-allergic inflammatory disease. The human TLRs comprise an important and interesting group of receptors that regulate pathogen-related responses, and play as yet uncharacterized roles in the amplication of sterile inflammation. Signalling through these receptors, which are power...

Telang, N.; Li, G.; Sepkovic, D.; Bradlow, H.Leon.; Wong, G.Y.C., 2014: Comparative efficacy of extracts from Lycium barbarum bark and fruit on estrogen receptor positive human mammary carcinoma MCF-7 cells. Chemo-endocrine therapy for estrogen receptor positive (ER(+)) breast cancer exhibits acquired tumor resistance. Herbal medicines provide integrative support for breast cancer patients. Present study compared the efficacy of aqueous extracts from...

Soda, G.; Grizzi, F.; Nardone, S.; Dioguardi, N.; Melis, M., 2001: Fractal quantitative evaluation of collagen matrix in liver biopsy specimens during chronic disease. Virchows Archiv 439(3): 268, September

Glebezdin, VS., 1986: New species of Coccoidea of Eimeria genus from Meriones erythrourus Gray in Turkmenistan. Izvestiya Akademii Nauk Turkmenskoi SSR Seriya Biologicheskikh Nauk, 4: 70-72

Li, C.D.; Han, Z.M.; Ye, J.R.; Zheng, W.P.; Zhang, Z.H.; Zheng, R.H.; Zhang, H.T., 1987: Development of brown-spot needle blight in slash pine plantations. A study of Lecanosticta acicola [Mycosphaerella dearnessii] spread in Pinus elliottii plantations in the N. region of Fujian province, China in 1982-85. [With English captions.].

Hewer, H.R., 1926: Studies in colour changes of fish. I. The action of certain endocrine secretions in the minnow. Adrenalin injected intramuscularly produces contraction of all chromatophores. The minimal dose for causing pallor over the whole body was .005 mgm.; but the minimal dose for causing localized pallor was .00005 mgm. This latter figure was regarded...

Wohlrab F.; Schmidt S.; Wilke B.; Cossel L., 1987: Proliferation of b cells in pancreatic islet syngeneic transplantation into the spleen of streptozotocin diabetic lewis rats. Diabetologia 30(7): 598A