geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Cocaethylene in meconium specimens


, : Cocaethylene in meconium specimens. Journal Of Toxicology Clinical Toxicology. 32(6): 697-703

Cocaethylene, a metabolite of cocaine and ethanol, exhibits cardiac and neurobehavioral effects. In order to determine the prevalence of this compound in meconium specimens, samples which gave a positive result for benzoylecgonine using fluorescence polarization immunoassay were analyzed by gas chromatography/mass spectrometry for cocaine, cocaethylene and benzoylecgonine. Deuterated cocaine, cocaethylene and benzoylecgonine were used as internal standards. Gas chromatography/mass spectrometry cutoff concentrations of 5.0 ng/g were utilized for all analyses. Of the 361 specimens which consecutively confirmed positive for cocaine or benzoylecgonine, 114 (31.6%) tested positive for cocaethylene. Further, cocaethylene accumulates in greater concentrations in meconium than urine, and is a useful analyte for identifying fetal alcohol exposure.

US$19.90

PMID: 7966527

DOI: 10.3109/15563659409017976


Other references

White John S., 2004: Taking it for granite. Rocks and Minerals 79(5): 349-350

Goesch, T.; Hanna, N., 2002: Efficient use of water: role of secure property rights. This paper raises some issues that Australian states need to consider when selecting the coverage and flexibility of a system of water property rights. The security of property rights (where security refers to the risks associated with the full or...

Thomas, J.A.; Delain, E.; Hollande, E., 1967: Morphogenesis of a hamster virus associated with the BHK strain or with tumors. Comptes Rendus Hebdomadaires des Seances de L'academie des Sciences. Serie D: Sciences Naturelles 264(5): 785-788

Wils, J., 1984: Chemotherapy of metastasizing stomach cancer. Deutsche Medizinische Wochenschrift 109(44): 1704-1704

Cannell, R.Q.; Ellis, F.B.; Barnes, B.T.; Henderson, F.K.G.; Elliott, J.G.; Pollard, F., 1977: Effects of reduced cultivation on soil conditions and root development of cereals. This was the 8th year of the joint project with the Weed Research Organization to compare the effects of direct drilling, fine cultivation and ploughing on winter wheat and spring barley grown on 3 contrasting soil types. On the sandy loam soil at...

Mozaffarian, D.; de Oliveira Otto, M.C.; Lemaitre, R.N.; Fretts, A.M.; Hotamisligil, G.; Tsai, M.Y.; Siscovick, D.S.; Nettleton, J.A., 2013: trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA). Dairy consumption is linked to a lower risk of type 2 diabetes, but constituents responsible for this relation are not established. Emerging evidence suggests that <I>trans</I>-palmitoleate (<I>trans</I> 16:1n–7), a f...

Moser, M.; Wüthrich, R., 1971: Care of patients with neurologic and other disorders in a day center. Day care center Egliseeholz of the Society for Public Welfare in Basel. Schweizerische Rundschau für Medizin Praxis 60(31): 1053-1054

Ho, P.L.; Yam, W.C.; Cheung, T.K.; Ng, W.W.; Que, T.L.; Tsang, D.N.; Ng, T.K.; Seto, W.H., 2001: Fluoroquinolone resistance among Streptococcus pneumoniae in Hong Kong linked to the Spanish 23F clone. Serotypes 6A/B, 19F, and 23F accounted for 73% of 140 mucosal isolates of Streptococcus pneumoniae from Hong Kong. In pulsed-field gel electrophoresis analysis, a group of related patterns was shared by 14 of 15 ciprofloxacin-resistant and 12 of 1...

Menzies, I.S., 1972: Urinary excretion of sugars related to oral administration of disaccharides in adult coeliac disease. Clinical Science 42(4): 18p-18p

Belde, M.; Mattheis, A.; Sprenger, B.; Albrecht, H., 2000: Long-term development of yield affecting weeds after the change from conventional to integrated and organic farming. The development of arable weed flora during the change from a conventional farming system (1990-92) to integrated and organic farming systems (1993-98) was investigated at Scheyern, Germany. The rotation in the integrated system was potatoes, wint...