+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Cooperative interaction of S. pombe proteins required for mating and morphogenesis

, : Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell 79(1): 131-141

We isolated two S. pombe genes, scd1 and scd2, that are required for normal morphology and mating. scd1 and scd2 are homologous to CDC24 and BEM1, respectively, of S. cerevisiae. Epistasis analyses indicate that scd2 and ras1 converge upon scd1, which, in turn, interacts with cdc42sp, a RHO-like GTPase. Studies with the yeast two-hybrid system indicate that scd2 forms complexes with both scd1 and cdc42sp. Furthermore, biochemical studies indicate that the interaction between scd1 and scd2 is direct. The yeast two-hybrid data further suggest that scd1, scd2, cdc42sp, and ras1, in its GTP-bound state, act cooperatively to form a protein complex. Copyright 1994 Cell Press.


PMID: 7923372

DOI: 10.1016/0092-8674(94)90406-5

Other references

Holter, H.; Zeuthen, E., 1944: The respiration of the egg and embryo of the ascidian, Ciona intestinalis L. The paper describes some observations on the biology and life-cycle of Ciona intestinalis, and it gives an account of the properties of Ciona-eggs and their suitability for micrurgical expts. The micrurgical isolation of single blastomeres and egg...

Suzuki J.B.; Vincent J.W.; Cornett W.C.; Falkler W.A.Jr, 1986: Reaction of human sera from untreated early onset periodontitis patients. Journal of Dental Research 65(SPEC ISSUE): 204

Glenn, E., 1977: Properties and subcellular distribution of two partially purified ornithine transcarbamoylases in cell suspensions of sugarcane. The spatially separated forms of ornithine transcarbamoylase (EC of different molecular weights coexist in sugarcane (Saccharum sp.). The smaller form of the enzyme (mol wt 79,000) appears to be cytoplasmic, while a larger form (mol wt 22...

Barriault, D.; Sylvestre, M., 1999: Functionality of biphenyl 2,3-dioxygenase components in naphthalene 1,2-dioxygenase. The authors determined the catalytic capacity of purified naphthalene 1,2-dioxygenase (Nap dox) toward chlorobiphenyls and investigated the functionality of biphenyl 2,3-dioxygenase (Bph dox) components in the Nap dox system. Nap dox and Bph dox a...

Yeo, L.; Adlard, N.; Biehl, M.; Juarez, M.; Smallie, T.; Snow, M.; Buckley, C.D.; Raza, K.; Filer, A.; Scheel-Toellner, D., 2016: Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis. For our understanding of the pathogenesis of rheumatoid arthritis (RA), it is important to elucidate the mechanisms underlying early stages of synovitis. Here, synovial cytokine production was investigated in patients with very early arthritis. Sy...

Gessmann, R.; Quanz, D.R.; Schulz, N., 1996: The Olympic spirit is still around - a review of the literature with an educational interest. The activities and events which have taken place in German schools during 1996 to commemorate the Centennial Olympic Games are described. The educational components of these activities are described and reviews of a selection of the major publicat...

Lee, M.C.; Lee, D.S.; Hyun, I.Y.; Chung, J.K.; Wang, K.C.; Cho, B.K.; Koh, C.S., 1996: Evaluation of surgical outcome with pre- and post-operative rest/diamox Tc-99m-HMPAO SPECT in children with Moyamoya disease. Journal of Nuclear Medicine 37(5 SUPPL ): 89P

Relf, P.D.ane; Silva, E., 1990: Clinging, climbing and twining: vines make a colorful addition to any landscape. American Nurseryman 171: 6-9

Sumenkova, V.; Ermicheva, F.; Yazlovetskii, I., 1990: Characterization of gut proteases of some species of Chrysopa with different feeding habits. Journal of evolutionary biochemistry and physiology 25(4): 301-306

Korytnikov, K.I.; Korneev, N.V.; Sal'vitskiĭ, B.N.; Zharkin, A.A.; Kazakova, I.G., 1987: Comparative evaluation of the ultrasonic and roentgenologic methods of examination in the diagnosis of post-infarct aneurysms of the heart. Voenno-Meditsinskii Zhurnal: 54-56