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Cyclical breast pain and swelling in relation to differing patterns of suppression of ovarian activity with the luteinizing hormone-releasing hormone analogue buserelin acetate: case report


, : Cyclical breast pain and swelling in relation to differing patterns of suppression of ovarian activity with the luteinizing hormone-releasing hormone analogue buserelin acetate: case report. Fertility and Sterility 63(1): 193-195

The presenting complaints of an amenorrhoeic (after hysterectomy with ovarian preservation) woman were cyclical breast pain and swelling. These showed synchronicity with fluctuations in E-2 levels. Both ovarian activity and symptoms initially responded to (after lag periods of approximately 40 days) daily SC injections of the LH-RH analogue buserelin acetate. After a break in treatment, the interval between reinitiation of therapy and suppression of E-2 levels was prolonged markedly, ovarian function being apparently resistant even to very large doses of the analogue.

US$19.90

PMID: 7805912

DOI: 10.1016/s0015-0282(16)57318-x


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