+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Decrease of norepinephrine and preservation of acetylcholine in the hypothalamus of VMH obese rats

, : Decrease of norepinephrine and preservation of acetylcholine in the hypothalamus of VMH obese rats. Brain Research Bulletin 36(1): 97-99

We investigated to find which types of neuronal disturbance in the hypothalamus are responsible for ventromedial hypothalamic nucleus (VMH) lesion-induced development of obesity. We found that in VMH-lesioned obese rats, the contents of norepinephrine (NE) and dopamine in the hypothalamus were selectively decreased, but that the serotonin and acetylcholine levels were unchanged from those in sham controls. Also, the content of NE in the lateral portion of the hypothalamus was decreased. Our results show that disturbance of the hypothalamic noradrenergic and dopaminergic neurons, but not of the serotonergic or cholinergic neurons, contributes to the development of VMH lesion-induced obesity.


PMID: 7882057

DOI: 10.1016/0361-9230(94)00173-X

Other references

Barr Sandra M.; White Chris E.; McLeod Malcolm J., 1997: Comagmatic volcanic and granitoid rocks of the northeastern Kingston Belt; a Silurian volcanic arc?--Les roches volcaniques et granitoides du nord-est de la ceinture de Kingston proviennent-elles d'un arc volcanique du Silurien?. Information Circular - Mineral Resources Branch Department of Natural Resources

Allen, R.C., 2015: Proliferation and arrest: the genetics of orbital disorders. Oculoplastic genetic diseases can be divided into eyelid, lacrimal, and orbital disorders. The purpose of this review is to develop a rational approach to the categorization of genetic diseases that affect the orbit and review the most recent deve...

Stachenfeld N.S.; Gleim G.W.; Nicholas J.A.; Coplan N.L., 1988: Variation in borg scale at lactate threshold. Medicine & Science in Sports & Exercise 20(2 SUPPL): S21

Duckworth, D.H.; Twort, F.W.; D'Herelle, F., 1976: "Who discovered bacteriophage?". Bacteriological Reviews 40(4): 793-802

Bethel, J.S.; Briggs, D.G., 1978: Forest tending in the tropics - a path between possibilities and necessities. A discussion of the relatively low yields obtained from most tropical forests, as a result of low exploitation and utilization percent of the standing timber in the absence of silvicultural treatment, with examples mainly from Costa Rica and Thail...

Kim, H.Keun.; Missiakas, D.; Schneewind, O., 2014: Mouse models for infectious diseases caused by Staphylococcus aureus. Staphylococcus aureus - a commensal of the human skin, nares and gastrointestinal tract - is also a leading cause of bacterial skin and soft tissue infection (SSTIs), bacteremia, sepsis, peritonitis, pneumonia and endocarditis. Antibiotic-resistan...

Matheny, K.B.; Aycock, D.W.; Curlette, W.L.; Junker, G.N., 1993: The coping resources inventory for stress: a measure of perceived resourcefulness. This article reviews previous studies with the Coping Resources Inventory for Stress (CRIS) and reports the results of a recent convergent/divergent study on six CRIS scales. CRIS scales have high internal consistency and test-retest reliabilities...

Wolf, P.A., 1986: Cigarettes, alcohol, and stroke. Effects of intake of alcohol on risk of developing stroke are discussed with reference to the findings of Gill et al. Associations between long-term use of cigarettes and the occurrence of stroke are examined.

Klastersky, J., 1986: Therapy with cisplatin and etoposide for non-small-cell lung cancer. Seminars in Oncology 13(3 Suppl 3): 104-114

Ferguson, A.; Carr, K.E.; Macdonald, T.T.; Watt, C., 1978: Hyper sensitivity reactions in the small intestine part 4 influence of allo graft rejection on small intestinal mucosal architecture a scanning electron microscope and transmission electron microscope study. The effect of a local delayed hypersensitivity reaction (allograft rejection) on small intestinal architecture was examined by using scanning electron microscopy of the mucosal surface. In isografts, regarded as a morphological basis for normality...