+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Diabetic control and progression of retinopathy in elderly patients: five-year follow-up study

, : Diabetic control and progression of retinopathy in elderly patients: five-year follow-up study. Journal of the American Geriatrics Society 42(2): 142-145

Objective: To assess whether control of diabetes mellitus is as important in the elderly as in young and middle-aged diabetic patients in terms of progression of retinopathy. Design: A 5-year longitudinal cohort study. Setting: Outpatient diabetic clinic. Patients: One hundred fourteen non-insulin-dependent diabetic patients (30 males, 84 females) gtoreq 60 years of age. Measurements: Retinopathy was checked at the beginning and end of the follow-up period. During the 5-year followup period, demographic variables, body mass index, HbA1c, blood pressure, and plasma lipids were monitored. Retinopathy was classified as follows: grade 0, no lesion; grade 1, non-proliferative retinopathy; grade 2, pre-proliferative retinopathy; grade 3, proliferative retinopathy. Progression of retinopathy during the 5-year follow-up was defined as an increase in its grade. Results: At the start of the study, 13% of the patients already had retinopathy, all of grade 1. The 5-year follow-up study showed that progression of retinopathy was 23.6% in all cases, 22.2% in those with grade 0 initially, and 33.3% in those with grade 1 initially. The progression rates of retinopathy as a function of the mean HbA1c during the follow-up were as follows: lower than 7%, 2%; 7-8%, 20%; 8-9%, 40%; more than 9%, 61%. Multiple logistic regression analysis showed that, of the parameters examined, only HbA1c was a significant risk factor for progression of retinopathy. Conclusions: Control of diabetes mellitus is the most important factor associated with prevention of progression of retinopathy in elderly patients.


PMID: 8126325

DOI: 10.1111/j.1532-5415.1994.tb04941.x

Other references

Embree, J.F., 1948: Anthropology in Indochina since 1940. American Anthropologist 50 Pt 1(4): 714-716

Euler, H.V.; Adler, E., 1934: Lyochrome in the pigmented epithelium of the eye. Extraction with acetone of the pigmented epithelium, but not of the retina, of the eyes of oxen yielded a green fluorescent solution which, on evaporation and treatment with water and ether, yielded an aqueous layer containing lyochrome and an eth...

Coineau, Y.; Theron, P.D.; Valette, C., 1997: An association of phaneres, probably constituting a novel system of acoustic communication in mites. Grandjeanicus gabonensis Coineau and Theron n. sp. shows a functional grouping of two setae and a trichobothrium at the extremity of its first pair of legs, which is interpreted as novel system of acoustic communication. A hair termed C, which has...

Beňová, L., 2017: The business of desire: "Russian" bars in Amman, Jordan. This paper discusses the type of work migrant women from the former Eastern European countries perform in nightclubs in Amman, Jordan. The fieldwork for this qualitative study was conducted in 2010 and is based on in-depth interviews with 13 women...

Golden, D.B.K.; Kwiterovich, K.A.; Friedhoff, L.; Valentine, M.D.; Kagey Sobotka, A.; Marsh, D.G.; Lichtenstein, L.M., 1993: Food allergy in normal adults. Journal of Allergy & Clinical Immunology 91(1 PART 2): 151

Barclay, D., 1959: Education: a turn for the wiser. Pediatrics 23(4): 759-760

Cornu, E.; Lacroix, P.; Virot, P.; Aldigier, J.C.; Praloran, P.; Christides, C.; Laskar, M., 1998: M-CSF serous rate evolution during post-transplantation days in a heterotopic heart graft model mice. On heterotopic heart graft in mice, aged 7 weeks (C3H and B57), we investigate the variations of Macrophage Colony stimulating factor serous rate. The macrophage colony stimulating factor (M-CSF) is a cytokine involved in the immune response durin...

Adler M.; Jakob A.; van Mazijk A., 1993: Hydraulic fundamentals. Bericht der KHR 12: 43-58

Gaeta, C.; Talotta, C.; Farina, F.; Campi, G.; Camalli, M.; Neri, P., 2011: Conformational features and recognition properties of a conformationally blocked calix[7]arene derivative. The shaping of a calix[7]arene macrocycle into cone-like structure 3, through exhaustive alkylation of doubly bridged calix[7]arene derivative 2 with bulky groups, has been investigated. Conformational details about the structure adopted by calix[...

Karam G.A.; Paynter K.T.; Bishop S.H., 1986: Ketoglutarate dehydrogenase from bivalve mollusk gill tissue absence of a marked calcium regulatory effect. Federation Proceedings 45(6): 1505