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Distribution of pleural injectate. Effect of volume of injectate and animal rotation


, : Distribution of pleural injectate. Effect of volume of injectate and animal rotation. Chest 106(4): 1246-1249

It is controversial whether rotation is necessary for patients undergoing pleurodesis. In addition, the optimal volume of the injectate remains to be determined. The purpose of this study was to determine the importance of rotation and the volume of the agent on the intrapleural dispersion of agents injected into the pleural space of rabbits. Technetium 99m pertechnetate (99mTc) in 0.5, 1.0, or 2.0 ml of saline solution was injected into ten lightly anesthetized rabbits, half of whom were rotated for 1 min after the injection. Static images were obtained in the anterior projection 1 and 5 min after the injection. After the second scan, the limits of the lung were defined by obtaining a perfusion scan immediately after the intravenous injection of macroaggregates of 99mTc-labeled serum albumin. The degree of dispersion was significantly greater in the nonrotated groups both at 1 min (F = 8.11, p = 0.0085) and at 5 min (F = 5.89, p = 0.0274). In addition, the homogeneity of the distribution of the injectate was not improved with rotation. From this study, we conclude that rotation of the animal for 1 min after the intrapleural injection does not improve the distribution of the injectate throughout the pleural space. Furthermore, a volume of 0.5 ml is sufficient for all pleural surfaces to be exposed.

US$29.90

PMID: 7924504


Other references

Shickley, T.; Pontari, M.; Luthin, G.R.; Ruggieri, M.R., 1993: Regional distribution of nitric oxide synthase, cholinesterase and muscarinic receptor subtypes in rat urinary bladder. Society for Neuroscience Abstracts 19(1-3): 90

Orem William H.; Lerch Harry E.; Bates Anne L.; Zielinski Robert A.; Corum Margo; Chrisinger Marisa, 2000: Nutrient and contamination in the South Florida ecosystem; synopsis of phase I studies and plans for phase II studies. Open-File Report - U S

Ma, G.; Jiang, X-Hua.; Chen, Z.; Ren, J.; Li, C-Rui.; Liu, T-Ming., 2007: Simultaneous determination of vitexin-4''-O-glucoside and vitexin-2''-O-rhamnoside from Hawthorn leaves flavonoids in rat plasma by HPLC method and its application to pharmacokinetic studies. The present study was to investigate the pharmacokinetics of the two similar flavonoid glycosides, vitexin-4"-O-glucoside (VGL) and vitexin-2"-O-rhamnoside (VRH) in rats after intravenous administration of hawthorn leaves flavonoids (HL...

Deitel M., 1989: Jejunocolic and jejunoileal bypass an historical perspective. Deitel, M (Ed ) Surgery For The Morbidly Obese Patient Xvi+400p Lea And Febiger: Philadelphia, Pennsylvania, Usa; London, England, Uk Illus 81-90

Montesinos Gonzalez, J., 1978: Types of pig and yields of different carcass cuts at a curing factory at Valdivia. For 86 pigs slaughtered in Chile, carcass weight averaged 92.15 kg, carcass length 82.13 cm, backfat thickness 3.68 cm and eye-muscle area 29.77 cm2. Carcass weight had a highly significant effect on the various carcass measurements.

Turcios-Ruiz, R.M.; Axelrod, P.; S.J.hn, K.; Bullitt, E.; Donahue, J.; Robinson, N.; Friss, H.E., 2008: Outbreak of necrotizing enterocolitis caused by norovirus in a neonatal intensive care unit. To investigate an outbreak of necrotizing enterocolitis (NEC) in a neonatal intensive care unit (NICU) and to identify the etiology, describe illness risk factors, and develop control measures. A retrospective case-control study was performed incl...

Levshina, I.P.; Pasikova, N.V.; Shuĭkin, N.N., 2005: Avoidance conditioning and morphometric characteristics of the sensorimotor cortex of rats exposed to social deprivation in early ontogeny. Male Wistar rats were exposed to social deprivation in the period from the 22nd to 70th days of postnatal development. The characteristics of the learning of these rats at the age 110-120 days in the passive avoidance box and during training for a...

Demain A.L., 1986: Recombinant dna and antibiotics a major advance. Bio-Technology (New York) 4(3): 175

Duan, S.; Wan, L.; Fu, W.J.; Pan, H.; Ding, Q.; Chen, C.; Han, P.; Zhu, X.; Du, L.; Liu, H.; Chen, Y.; Liu, X.; Yan, X.; Deng, M.; Qian, M., 2009: Nonlinear cooperation of p53-ING1-induced bax expression and protein S-nitrosylation in GSNO-induced thymocyte apoptosis: a quantitative approach with cross-platform validation. Increasing evidence has been gathered for p53-dependent apoptosis, but it is still unclear how p53 initiates apoptosis by employing its transcriptional program. Pair-wise interactions of p53 with expression of other genes fail to predict p53 level...

Silva, A.R.Da., 1950: Basis for a national plan of wheat research. Under genetics, determination of the biotypes of the main pathogens and the inheritance of resistance to them come highest in the list of subjects requiring study in Brazil.