geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effect of BCG-PSN on level of interleukin 2 and tumor growth of bearing S180 sarcoma mice


, : Effect of BCG-PSN on level of interleukin 2 and tumor growth of bearing S180 sarcoma mice. Acta Academiae Medicinae Hubei 18(4): 305-307, Oct

Polysaccharides nucleic acid fraction of BCG (BCG-PSN) and tumor necrosis factor alpha (TNF-alpha) were used to treat bearing S180 sarcoma mice. It has been confirmed that both BCG-PSN and TNF-alpha can inhibit the growth of S180 solid sarcoma significantly, the inhibitory rates were 58.10% and 36.25% respectively. The level of interleukin 2 of splenocytes appeared to be in positive linear correlation with the inhibitory rates. BCG-PSN can also markedly prolong the living period of bearing S180 ascites sarcoma mice. TNF had no sinergistic antitumor activity in combination with BCG-PSN and the efficiency of inhibiting tumor growth of TNF was lower than that of BCG-PSN due to its side-effect, whereas BCG-PSN did not appear to produce any side-effect in this study.

US$29.90


Other references

Sudare, T.; Ueno, T.; Watthanaphanit, A.; Saito, N., 2015: Verification of Radicals Formation in Ethanol-Water Mixture Based Solution Plasma and Their Relation to the Rate of Reaction. Our previous research demonstrated that using ethanol-water mixture as a liquid medium for the synthesis of gold nanoparticles by the solution plasma process (SPP) could lead to an increment of the reaction rate of ∼35.2 times faster than that i...

Annicchiarico, P.; Piano, E., 1997: Response of white clover genotypes to intergenotypic and interspecific interference. Six white clover genotypes that were easily distinguishable from each other on the basis of leaf lamina marks and morphology were grown at Lodi, Italy, during 1990 and 1991 in dense swards, under field conditions and a mowing regime, as (i) pure s...

Havsteen, H.; Kjaer, M., 1996: Antiemetic treatment with two different doses of methylprednisolone in breast cancer patients: a double-blind randomized cross-over study with evaluation of efficacy parameters. This randomized double-blind cross-over study followed a previous one which showed an antiemetic efficacy from methylprednisolone (MP) 250 mg superior to placebo. The present study compared MP 40 mg with 250 mg in breast cancer patients treated wi...

Stoner, D., 1921: Bird banding and incidental studies. Proceedings of the Iowa Academy of Science, 28: 151-159

Betina J.L.movasky; Ana Baldoni; Pablo Ribeiro; Graciela Alvarez; Mario Lasta; Silvana Campodónico; Oscar Iribarne, 2011: Exploring the causes of differences in growth rate of the Patagonian scallop Zygochlamys patagonica along its commercial bed distribution in the SW Atlantic. Comparisons of maximum age and growth rates of the Patagonian scallop Zygochlamys patagonica from seven beds across most of its distribution range (39 3'S to 46 47'S; SW Atlantic) were studied in relation with physical parameters and Chl...

Bandiera, G.; Antognetti, P.F., 1954: Analytical cardiac roentgenkymography. III. Study of atrial arrhythmias. Archivio "e. Maragliano" di Patologia E Clinica 9(5): 1269-1291

Oakenfull, D., 1978: Dietary fibre, serum cholesterol and heart disease. CSIRO food research quarterly 38(3): 66-70

Popova, L.M.; Morgunov, V.A., 1974: Polyneuropathy in acute intermittent hepatic porphyria following resuscitation. Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 74(11): 1609-1614

Richter, A.; Loeschmann, P.A.; Loescher, W., 1996: Antidystonic effects of inhibitors of nitric oxide synthase in genetically dystonic hamsters. Society for Neuroscience Abstracts 22(1-3): 1649

Gallina, G.; Cumbo, V.; Messina, P.; Caruso, C., 1985: Recurrent aphthous stomatitis and HLA-DR7 antigen: a possible association. Minerva Stomatologica 34(5): 735-740