+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of ginsenosides on impaired performance induced in the rat by scopolamine in a radial-arm maze

, : Effects of ginsenosides on impaired performance induced in the rat by scopolamine in a radial-arm maze. Psychoneuroendocrinology. 20(6): 645-653

The effects of ginsenosides Rg1, Rd and Rb1 on impaired performance induced in the rat by scopolamine were examined in a radial-arm maze. Scopolamine caused a reduction in the number of initial correct responses in the maze. A single IP injection of Rg1, but not Rd or Rb1, prevented the reduction. The inhibition of the reduction in initial correct responses was associated with a bellshaped dose-response curve for Rg1. A lesion in the medial septum caused spatial learning deficits. Rg1 did not overcome these deficits. It is suggested that cholinergic neurons in the medial septum are involved in the ameliorative effect of Rg1 on impaired performance induced by scopolamine.


PMID: 8584605

DOI: 10.1016/0306-4530(95)00008-c

Other references

Evers, AMJ., 1989: Gattungssystematik auf Grund der Evolution der Malachiidae, ein Weg zur naturlichen System. Internationales Symposium ueber Entomofaunistik in Mitteleuropa, 11: 224-227

Bawa, V.; Fallat, L.M.; Kish, J.P., 2016: Surgical Outcomes for Resection of the Dorsal Exostosis of the Metatarsocuneiform Joints. A retrospective case series testing the efficacy of surgical resection of the dorsal exostosis deformity of the metatarsocuneiform joints was performed. Surgery was performed in 26 consecutive patients (28 feet), in whom previous conservative ther...

A.L.Bakke., 1937: Control of leafy spurge, Euphorbia Esula L. This bulletin contains the results of experiments on the eradication of leafy spurge (Euphorbia Esula L), which is a serious weed on many Iowa farms. The herbicidal treatments included the use of sodium chlorate, Atlacide, creosote-kerosene, sulfu...

Fricker M.D.; White N.S., 1992: Wavelength considerations in confocal microscopy of botanical specimens. Journal of Microscopy (Oxford) 166(1): 29-42

Teltsh, O.; Kanyas, K.; Karni, O.; Levi, A.; Korner, M.; Ben-Asher, E.; Lancet, D.; Hamdan, A.; Lerer, B.; Kohn, Y., 2007: Genome-wide linkage scan, fine mapping, and haplotype analysis in a large, inbred, Arab Israeli pedigree suggest a schizophrenia susceptibility locus on chromosome 20p13. Linkage and association studies in schizophrenia have repeatedly drawn attention to several chromosomal regions and to genes within them. Conflicting patterns of association and the lack of a clear functional significance of the associated variant...

Higaki, A.; Namba, K.; Watanabe, E.; Nemoto, S.; Gomi, A., 2015: Embolization for Refractory Subacute Subdural Hematoma in a Child with Severe Hemophilia Type A. Hemophilia is an X-linked hemorrhagic disease due to coagulation factor VIII or IX deficiency with approximately 5-10% incidence of central nervous system bleeding. We present an intriguing case of a refractory subacute subdural hematoma (SDH) con...

Bessoule J J.; Lessire R.; Cassagne C., 1990: Theoretical and experimental study of membrane bound enzyme activities involved in the lipid metabolism. Quinn, P J And J L Harwood (Ed ) Plant Lipid Biochemistry, Structure And Utilization; Ninth International Symposium on Plant Lipids, Kent, England, Uk, July 8-13, Xviii+483p Portland Press Ltd : London, England, Uk Illus 145-147

Fox, A.; Kang, N., 2008: Reinserting the central slip - a novel method for treating boutonniere deformity in rheumatoid arthritis. Journal of Plastic, Reconstructive & Aesthetic Surgery 62(5): E91-E92

Wlodek, Stanislaw, 1964: Radioactivity of one series of aquatic and terrestial organisms in relation with the radioactivity of their surrounding environment. Ekol Polska Ser A 12(26): 415-427

Dukovski, D.; Bernatzky, R.; Han, S., 2004: Isolation of ethylene-responsive genes involved in flowering of Guzmania lingulata Anita. Hortscience 39(2): 457, April