+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Elicitation of Alexandrium ostenfeldii (Dinophyceae) affects the toxin profile

, : Elicitation of Alexandrium ostenfeldii (Dinophyceae) affects the toxin profile. Comparative Biochemistry and Physiology C Pharmacology Toxicology and Endocrinology 111(3): 405-412

Batch cultures of the dinoflagellate Alexandrium ostenfeldii (Paulsen) Balech et Tangen were characterized by an exponential growth phase ending after 10 days. Three different paralytic shellfish poison (PSP) toxin patterns (A, B, and C) occurred at days 3, 6 and 10, respectively. The main toxins in pattern A were: 53% GTX6, 26% C4, 17% GTX5; B: 62% GTX4, 17% GTX6, 16% C3; C: 31% GTX4, 28% GTX6, 26% C4, 13% C3. Batch cultures (with identical pattern A) were challenged (elicted) on day 3 with various organic compounds and extracts of Alexandrium tamarense. After elicitation each toxin concentration changed on both day 6 and 10. A causal relation between properties of the elicitor and the resulting toxin pattern could not be established. It is proposed that toxins responding with small relative standard variations from the mean concentration (STX, neoSTX, GTX3, GTX4, GTX6 and C3) are characteristic for the batch culture. Toxins with high variability (GTX1, GTX2, GTX5, C2 and C4) change concentration as a result of stress provoked by the elicitors. The toxicity (estimated from standard values) of some elicited cultures had increased by a factor of 4 on day 10 indicating that stimulation of blooms of A. ostenfeldii may have substantial consequences regarding the problem of paralytic shellfish poisoning.


DOI: 10.1016/0742-8413(95)00067-4

Other references

Dugan, C.C., 1976: A new look at gene determinants and their controls. Journal of the Florida Medical Association 63(1): 29-31

Hoffmann F.; Buechner M., 1977: Lead determination in whole blood and urine with the flame atomic absorption spectrophotometer. Zeitschrift fuer Medizinische Laboratoriumsdiagnostik 18(1): 51-52

Linnell, J.W.; Keynes, G.; Piercy, J.E., 1946: Some Vulgar Errors in Regard to Goitre. British Medical Journal 2(4473): 449-452

Kaneko, T.; Matsubayashi, T.; Sugita, M.; Sugiura, M., 1996: Physical and gene maps of the unicellular cyanobacterium Synechococcus sp. strain PCC6301 genome. A physical map of the unicellular cyanobacterium Synechococcus sp. strain PCC6301 genome has been constructed with restriction endonucleases PmeI, SwaI, and an intron-encoded endonuclease I-CeuI. The estimated size of the genome is 2.7 Mb. On the...

Egert, G.; Greim, H., 1976: Formation of mutagenic N-nitroso compounds from the pesticides prometryne, dodine and carbaryl in the presence of nitrite at pH 1. Environmental chemicals including pesticides carrying secondary and tertiary amino groups are suggested to be a health hazard to man since potentially carcinogenic nitroso compounds may be formed in the presence of nitrite at low pH values resembl...

Spence, A.A.; Ellis, F.R., 1970: A critical evaluation of a nitrogen rebreathing method for the estimation of Pv02. Respiration Physiology 10(3): 313-320

Stringer, M.D., 2013: The internal vertebral venous plexus. Clinical Anatomy 25(7): 912; Author Reply 913-912; Author Reply 913

Castaneda, J.L.; Quintero, A., 1991: Regulation of phenylalanine ammonia lyase pal ec activity by light in gomphrena globosa tissue culture. We describe the activation of phenylalanine ammonia-lyase (PAL) under different light conditions, in Gomphrena globosa tissue culture. PAL activity is induced under blue and white light; PAL activation under blue light is higher than under other l...

Mori, K.; Horino, M., 1997: The effect of perceived social support and achievement motive on hopelessness. The purpose of this study was to investigate the effect of achievement motive on the relationship between perceived social support and hopelessness in elementary school children. Two surveys were administered. The first examined the reliability an...

von Schacky, C., 2012: The Omega-3 Index as a risk factor for cardiovascular diseases. The Omega-3 Index has been defined as eicosapentaenoic plus docosahexaenoic acids in erythrocytes. Integral part of the definition is a standardized analytical procedure, which conforms to the standards of Clinical Chemistry. This resulted in more...