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Exposure of CHO cells to AluI: Comparison of chromosomal aberrations and cell survival

, : Exposure of CHO cells to AluI: Comparison of chromosomal aberrations and cell survival. Mutation Research 326(2): 171-174

Chinese hamster ovary (CHO) cells were exposed to various doses of the restriction endonuclease AluI in the presence of 2.2 M glycerol. Some of the cells were cultured for analysis of chromosomal aberrations and some for analysis of colony-forming ability. Cell killing is mainly mediated by chromosomal aberrations.


PMID: 7529881

DOI: 10.1016/0027-5107(94)00169-6

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