geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Extraocular muscles in congenital strabismus: muscle fiber and nerve ending ultrastructure according to different regions


, : Extraocular muscles in congenital strabismus: muscle fiber and nerve ending ultrastructure according to different regions. Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift für Augenheilkunde 205(1): 29-39

The ultrastructure of the extraocular muscles of patients affected by congenital strabismus is not completely known, and the structures responsible of the pathogenesis of this condition are still to be determined. Specimens obtained from patients suffering from congenital strabismus were studied and compared with specimens obtained from patients enucleated for various pathologies and not affected by any disorder in the oculomotor system. The scleral myotendinous junction, where the occurrence of an altered proprioceptive innervation was already reported, was examined, and findings obtained were compared with those observed in the muscle body (venter), where motor innervation is prominent and usually described as normal. Only a small number of damage muscle fibers was found everywhere. The damage consisted in alterations of both contractile structures and mitochondria and resulted in severer lesions in the scleral myotendinous junction rather than in the muscle body. The normal muscle muscle fibers were innervated by motor nerve endings with normal features and by few altered proprioceptors. The less damaged muscle fibers were innervated by normal motor nerve endings and severely damaged proprioceptors. The most severely damaged muscle fibers did not receive any type of innervation. These data seem to imply that the most important functional. These data seem to imply that the most important functional alteration in strabismus regards the scleral myotendinous junction. It is the authors' opinion that these findings might have a clinical importance in choosing the treatment to be pursued in patients with a squint.

US$29.90

PMID: 1436989


Other references

Durr F.E.; Solosky J.; Citarella R.V.; Lindsay H.L., 1978: In vitro studies with a new anti viral compound 3 1 3 phenanthrylethylidene carbazic acid ethyl ester cl 91969. Abstracts of the Annual Meeting of the American Society for Microbiology 78 : 7

Zhao, L-di.; Li, J-ling.; Wang, Y.; Wang, B.; Wang, H-yu.; Hao, X-zhi.; Cui, C-xu.; Zhang, X-ru.; Shi, Y-kai., 2012: Factors affecting the sensitivity of EGFR-TKI treatment in advanced non-small cell lung cancer. To explore the clinical factors affecting the sensitivity of EGFR-TKI treatment in advanced non-small cell lung cancer. Clinical data were retrospective analyzed to determine the clinical factors affecting the outcome of 166 patients with advanced...

Gupta V.P.; Samad A.; Naqvi Q.A., 1988: Studies on the reduction in infectivity of spinach mosaic virus by metacid systemic insecticide. Metacid 50 (methyl parathion) inhibited the spinach mosaic virus both in vitro and in vivo. In the former the percentage inhibition was 67 per cent and in later 89 per cent when bioassayed on Chenopodium amaranticolor Coste and Reyn. Both pre-inoc...

Chikatunov, V.; Pavlicek, T., 2005: Leaf beetles (Coleoptera: Chrysomelidae) of the west and southwest facing slopes in the Israeli part of the Hermon Mountains. Unknown

Fujimoto, N.; Honda, H., 2003: Effects of environmental estrogenic compounds on growth of a transplanted estrogen responsive pituitary tumor cell line in rats. The modifying effects of three endocrine disrupting chemicals on the promotion phase of estrogen dependent tumor development were investigated with a transplantable rat pituitary cell line, MtT/E-2. The EDCs examined were genistein (Gen), a phytoe...

Romero J.; Sun S.M.; Bliss F.A.; Hall T.C., 1975: Heritable differences in phaseolus vulgaris globulin poly peptides. Plant Physiology (Rockville) 56(2 SUPPL): 88

Mota Palomino R.; Andrieux J.; Bonnin J., 1986: The seismotectonic zone of southern Mexico. Geofisica Internacional: , Pages 207-231. 1986.

Cummins T.R.; Donnelly D.F.; Haddad G.G., 1990: Effect of histotoxic anoxia on hypoglossal neurons studied by whole cell patch clamp. Society for Neuroscience Abstracts 16(2): 1061

Dusart, I.; Flamant, F., 2012: Profound morphological and functional changes of rodent Purkinje cells between the first and the second postnatal weeks: a metamorphosis?. Between the first and the second postnatal week, the development of rodent Purkinje cells is characterized by several profound transitions. Purkinje cells acquire their typical dendritic "espalier" tree morphology and form distal spines....

Rutanen, I., 1989: Mordella brachyura Mulsant in Finland (Mordellidae) (SHS 20.1.1989).. Notulae Entomologicae, 694: 213