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Fetal tissue typing in anticipation of neonatal heart transplantation


, : Fetal tissue typing in anticipation of neonatal heart transplantation. Obstetrics & Gynecology. 91(5 Part 2): 823-825,

Background: Hypoplastic left heart syndrome is among the most common major congenital cardiac anomalies. Fetuses with this anomaly survive but require either reconstructive surgery or heart transplantation postnatally. Case: A woman whose fetus was diagnosed with hypoplastic left heart syndrome underwent funipuncture for fetal tissue typing. The fetus then was listed for heart transplantation. Once an ABO-compatible donor heart was procured, the fetus was delivered and immediately underwent transplantation. Conclusion: In candidates for neonatal heart transplantation, fetal tissue typing allows the search for an ABO-compatible donor heart to begin earlier. This approach minimizes the morbidity associated with postnatal waiting and allows transplantation to take place while the neonate is less immunocompetent.

US$19.90

PMID: 9572176

DOI: 10.1016/s0029-7844(97)00480-8


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