geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Hydrocephalus associated with intramedullary low-grade glioma. Illustrative cases and review of the literature


, : Hydrocephalus associated with intramedullary low-grade glioma. Illustrative cases and review of the literature. Journal of Neurosurgery 83(3): 480-485

Over the past 15 years, eight children affected by intramedullary low-grade gliomas associated with hydrocephalus were treated at l'Hôpital des Enfants Malades. In all cases the diagnosis of hydrocephalus was made prior to that of the spinal tumor. Neuroradiological examination of all patients revealed contrast enhancement of the intracranial subarachnoid spaces. In six cases this was progressive, suggesting subarachnoid spread of the tumor, which was confirmed in two cases by histological examination. The authors analyzed 38 cases of intramedullary low-grade glioma associated with hydrocephalus that were reported in the literature. Fifteen of the cases had intracranial leptomeningeal seeding. Several hypotheses have been proposed to explain this unusual association, such as 1) increase in cerebrospinal fluid (CSF) viscosity because of elevated fluid protein content; 2) obliteration of the cisterna magna due to a rostral extension of the tumor; and 3) blockage of the spinal subarachnoid pathways of CSF resorption. Two other theories seem of particular interest. Bamford and Labadie suggested that the abnormal presence of fibrinogen in the CSF and its transformation into fibrin at the level of the basal cisterns and Pacchioni's granulation may alter CSF hydrodynamics. This mechanism alone is sufficient to induce hydrocephalus of the communicating type. In addition, as suggested by Maurice-Williams and Lucey, the resulting leptomeningeal fibrosis might predispose secondary implantation of neoplastic elements in the subarachnoid spaces of the intracranial compartment.

US$19.90

PMID: 7666226

DOI: 10.3171/jns.1995.83.3.0480


Other references

Williams, N.; Pluznik, D.H., 1978: Differences in the buoyant density characteristics of murine granulocyte-macrophage progenitor cells cloned in the presence of serum and/or hemolysate. Bone marrow-derived progenitor cells of granulocytes and macrophages undergo proliferation and maturation in vitro in the presence of colony-stimulating factors and suitable sera. It has recently been found that rat hemolysate can replace serum as...

Anonymous, 1941: Erratum: Materia Medica of Pharmaceutical Combinations and Specialities. [This corrects the article on p. 440b in vol. 76.].

Oda, T.; Panjabi, M.M.; Crisco, J.J.; Bueff, H.U.; Grob, D.; Dvorak, J., 1992: Role of tectorial membrane in the stability of the upper cervical spine. The purpose of this in vitro experimental study was to determine the role of the tectorial membrane in providing stability to the upper cervical spine. Five fresh human cadaveric specimens from the occiput to C-3 were studied with a flexibility pr...

Jain, R.Singh.; Gupta, A.; Gupta, P.Kumar.; Agrawal, R., 2016: Periodic electroencephalogram discharges in a case of Lafora body disease: An unusual finding. Lafora body disease (LBD) is a form of progressive myoclonic epilepsy, characterized by seizures, myoclonic jerks, cognitive decline, ataxia, and intracellular polyglucosan inclusion bodies (Lafora bodies) in the neurons, heart, skeletal muscle, l...

Dierschke D.J.; Bhattacharya A.N.; Atkinson L.E.; Knobil E., 1970: Circhoral oscillations of plasma luteinizing hormone levels in the ovariectomized rhesus monkey. Endocrinology 87(5): 850-853

Anonymous, 1947: The bacteriology of spray-dried egg with particular reference to food poisoning. (Med. Res. Counc. Spec. Rep. Ser. No. 260). This report, consisting of a comprehensive collection of papers on the bacteriology of spray-dried egg, covers the general bacteriology of the egg powder, but the bulk of the report is concerned with the importance of contamination of the powder w...

Zadara, M., 1977: Some notes on rare representatives of mucorales. Four rare specimens of Mucorales are discussed: Mycotypha microspora, Syncephalis nodosa, Chaetostylum venustellum and Coemansia thaxteri.

Raz, A.; Pienta, K.J., 1999: Method for treatment of cancer by oral administration of modified pectin. A method for the treatment of cancer in mammals. A subject afflicted with cancer receives by oral administration a pH modified citrus pectin which inhibits metastasis of primary tumors. This invention was made with Government support, under Contra...

Anonymous, 1962: Male sterility as an aid to hybrid seed production. Foliar spraying with a 0.15% aqueous solution of FW-450 (sodium dichloroisobutyrate) caused development of a non-heritable type of male sterility in Gossypium hirsutum variety H. 14, which lasted throughout the entire blossoming period of 5-6 week...

Friedman, S.; Gibbons, J.; Galvan, C., 2016: Declining segregation through the lens of neighborhood quality: does middle-class and affluent status bring equality?. Middle- and upper-class status along with suburban residence are together considered symbolic of the American dream. However, the question of whether they mean access to better quality residential environments has gone largely unexplored. This stu...