geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Hydroxyapatite in experimental laryngotracheal reconstruction


, : Hydroxyapatite in experimental laryngotracheal reconstruction. Archives of Otolaryngology--Head & Neck Surgery 119(1): 87-91

Current concepts in laryngotracheal reconstruction include lumen augmentation with interposition of autogenous costal cartilage. In an effort to reduce potential increased morbidity at the donor site, the use of porous hydroxyapatite was compared with autogenosu costal cartilage in an experimental study. Ninety-nine New Zealand rabbits were randomly operated on to receive autogenous costal cartilage (n = 32), hydroxyapatite covered by a perichondrium graft (n = 33), or hydroxyapatite alone (n = 34). Rabbits were killed at 3 months after the surgery. Clinically (n = 85), no difference was found among the groups. Histologically (n = 81), grafts (n = 54) in the group receiving autogenous costal cartilage were greater than in those receiving the hydroxyapatite. Concerning the value of epithelial layer covering the graft, the rate of inflammation, the cricoid-graft interface, and the graft viability, no difference was noted among the groups. In the group in which no graft was found (n = 27), a fibrous bridge maintaining a cricoid distraction was noted in 23 cases. This study shows the possible value of hydroxyapatite in the animal model, but before clinical application, the natural course of the fibrous bridge must be documented.

US$19.90

PMID: 8380247

DOI: 10.1001/archotol.1993.01880130089013


Other references

Dalçik, H.; Yardimoglu, M.; Filiz, S.; Gonca, Süheyla.; Dalçik, C.; Erden, B.Faruk., 2010: Chronic ethanol-induced glial fibrillary acidic protein (GFAP) immunoreactivity: an immunocytochemical observation in various regions of adult rat brain. In the present study, the effects of chronic ethanol (ETOH) treatment on the glial fibrillary acidic protein (GFAP) immunoreactivity was investigated in adult rat brains. ETOH were administered as increasing concentrations of 2.4%-7.2% (v/v) gradu...

Romeuf, M.; Proux, J.; Remy, C., 1986: The neurophysin-vasopressin-like system in migratory locust embryos. Immunohistological and radioimmunological studies. Using immunohistology and radioimmunoassay (RIA), we detected an early synthesis of the neurosecretory product related to vasopressin-neurophysin in the central nervous system of locust embryos. Both techniques gave similar results. By means of im...

Czeczuga, B.; Czerpak, R., 1968: Carotenoids in Hydryphantes dispar (Schaub, 1888) (Hydracarina, Arachnoidea). In extracts separated by means of column and thin-layer chromatography the following carotenoids were identified in Hydryphantes dispar: -carotene, echinenone, canthaxanthin, lutein, neoxanthin (?) and one unknown xanthophyll.

Zhang, M.; Wang, J.; Li, L.; Zheng, G.; Liu, K.; Qin, M.; Zhou, H.; Zhan, X., 2017: High-Mobility p-Type Organic Semiconducting Interlayer Enhancing Efficiency and Stability of Perovskite Solar Cells. A high-mobility p-type organic semiconductor based on benzodithiophene and diketopyrrolopyrrole with linear alkylthio substituents (BDTS-2DPP) is used as a dual function interfacial layer to modify the interface of perovskite/2,2',7,7'-t...

Foubister, V.; Rosenshine, I.; Finlay, B.B., 1994: A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells. Enteropathogenic Escherichia coli (EPEC) is a bacterial pathogen that causes diarrhea in infants by adhering to intestinal epithelial cells. EPEC induces host cell protein phosphorylation and increases intracellular calcium levels that may functio...

Munir, M.Bilal.; Althouse, A.D.; Rijal, S.; Shah, M.Bharat.; Abu Daya, H.; Adelstein, E.; Saba, S., 2016: Clinical Characteristics and Outcomes of Older Cardiac Resynchronization Therapy Recipients Using a Pacemaker versus a Defibrillator. Cardiac resynchronization therapy (CRT) is commonly used to manage heart failure, yet published guidelines do not distinguish between recommendations for pacemakers (CRT-P) and defibrillators (CRT-D) despite significant differences in size, longev...

Apostolov, B.G.; Sokolova, M.I.; Samarina, G.Ia.; Beliaeva, G.Ia., 1975: Study of gastric secretion with the use of pentagastrin in children with diseases of the stomach and duodenum. Voprosy Okhrany Materinstva i Detstva 20(12): 11-14

Shats, V.Ia., 1971: The concept of immunologic privilege in oncology and transplantology (review of the foreign literature). Voprosy Onkologii 17(5): 100-109

dell'Uomo, G.; Gippoliti, S., 1995: Captive breeding and preservation of endangered birds. Supplemento alle Ricerche di Biologia della Selvaggina 22. (Marzo)

Landsberg D.; Chiu A.; Werb R.; Taylor P.; Chan Yan C.; Manson A.D., 1988: The effect of triple therapy on cyclosporine cya nephrotoxicity and hypertension in renal transplantation rtx. Clinical & Investigative Medicine 11(4 SUPPL): C115