geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Hypoenergetic nutrition support in hospitalized obese patients: a simplified method for clinical application


, : Hypoenergetic nutrition support in hospitalized obese patients: a simplified method for clinical application. American Journal of Clinical Nutrition 66(3): 546-550

Nutrition support in obese hospitalized patients is controversial,: with some practitioners advocating restricted energy or hypoenergetic feedings when patients are being actively treated for another disease. To eliminate the need for indirect calorimetry, this randomized, double-blind, prospective study was undertaken to determine whether obese hospitalized patients given a hypoenergetic parenteral regimen administered to provide 2 g protein cntdot kg ideal body wt (EBW)-1 cntdot d-1, could achieve nitrogen balance comparable with that of control subjects given isonitrogenous normoenergetic formula. Thirty obese hospitalized patients with an average body mass index (BMI; in kg/m-2) of 35 were randomly assigned to the hypoenergetic (energy (kJ):nitrogen (g) = 314:1; energy (kcal):nitrogen (g) = 75:1; n = 16) or control (energy (kJ):nitrogen (g) = 628:1; energy (kcal):nitrogen (g) = 150:1; n = 14) formulas. The initial formula volume administered provided 2 g protein cntdot kg IBW-1 cntdot d-1. Nitrogen balance was determined on day 0 and weekly. The total daily energy intake (per kg actual body weight (ABW)) was 57 +- 12 kJ (hypoenergetic) compared with 94 +- 21 kJ (control), P lt 0.001, and the nonprotein energy intake was 36 +- 10 kJ (hypoenergetic) compared with 73 +- 17 kJ (control), P lt 0.001. Protein intake was the same per ABW, 2.0 +- 0.2 and 2.0 +- 0.1 g kg IBW-1 cntdot d-1, NS, for the hypoenergetic and control formulas, respectively. Mean net nitrogen balance was not significantly different between the Groups, even after patients were subgrouped by illness, nor was the percentage of patients achieving positive nitrogen balance. Duration of treatment averaged 10.5 +- 2.6 d. Weight change did not differ significantly between groups. These data indicate that patients receiving hypoenergetic feedings providing 2 g protein cntdot kg IBW-1 cntdot d-1 achieved nitrogen balance comparable with patients given conventional total parenteral nutrition regimens, even when critically ill.

US$19.90

PMID: 9280171

DOI: 10.1177/0148607197021006366


Other references

Fischer, Z., 1976: Nitrogen conversion in carp cyprinus carpio. The aim of this study was to investigate N and protein budgets in carp under laboratory conditions. Determinations were made in food, solid and liquid excretion and, after the experiment, also in the fish body. Assimilation of protein by carp is v...

Al-Shehbaz, Ihsan, A., 2006: Sisymbrium lactucoides belongs to Dictyophragmus (Brassicaceae). A critical comparison of the type collection of the Peruvian Sisymbrium lactucoides with members of that genus worldwide reveals that the species should be assigned to Dictyophragmus. The new combination D. lactucoides is proposed. A key to the th...

byford, R.L.; Riner, J.L.; Kocan, K.M.; Stratton, L.G.; Hair, J.A., 1981: Chemoprophylaxis of vector-borne anaplasmosis with sustained-release boluses. Sustained-release oxytetracycline boluses (20%) delivering 145 to 150 mg/bolus/day were administered to complement-fixation test-negative cattle at dosages of 2.0, 2.5, and 3.0 mg/kg of body weight. Subsequent challenge exposure of cattle with Der...

Meyskens, F.Jr, 1983: Vitamin A and synthetic derivatives (retinoids) in the prevention and treatment of human cancer. A review briefly summarizes laboratory, epidemiological, and clinical studies on the utility of vitamin A and synthetic retinoids for preventing and treating human cancer, and then summarizes and discusses clinical studies conducted at the author&...

Meanwell N.A.; Fleming J.S.; Russell J.W.; Seiler S.M., 1992: Bmy 43351 platelet camp phosphodiesterase inhibitor platelet aggregation inhibitor. Drugs of the Future 17(1): 15-17

Oranskiĭ, I.E.; Kochergin, I.V.; Khasanova, G.N., 2013: Heath status and level of adaptation in workers of the aluminium industry and technologies of the restorative medicine. The results of the research of states of adaptation and health in workers of the aluminum industry are provided. Functional connection of the level of adaptability in respect of the parameter of adaptation (AP) with the length of employment has be...

Dubielzig, R.R., 1977: Pulmonary lesions of neo natal foals. The histories, gross pathological descriptions and histopathological findings were reviewed for 37 foals which had died on or before 5 days of age. The lungs of 34 animals had recognizable lesions. Foals (22) exhibited infectious inflammatory lung...

Yehuda Cohen T.; Powell J.D.; Mcclure H.M.; Anderson D.; Fultz P.N.; Sell K.W.; Ansari A.A., 1989: Antigen processing requirements for the in vitro proliferation to siv by t cells from naturally infected mangabeys and siv infected macaques. FASEB Journal 3(4): A961

Saab, A.S.; Tzvetanova, I.D.; Nave, K-Armin., 2014: The role of myelin and oligodendrocytes in axonal energy metabolism. In vertebrates, the myelination of long axons by oligodendrocytes and Schwann cells enables rapid impulse propagation. However, myelin sheaths are not only passive insulators. Oligodendrocytes are also known to support axonal functions and long-te...

Bouricha, M.; Samad, M.Abdul.; Levy, P-Yves.; Raoult, D.; Drancourt, M., 2014: Point-of-care syndrome-based, rapid diagnosis of infections on commercial ships. Suspicion of contagious disease on commercial ships tends to be poorly managed, as there is little capacity to confirm a case on board except for malaria. Here we implemented a point-of-care (POC) laboratory on one container ship and one cruise sh...