+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

ICAM-1 tissue overexpression associated with increased serum levels of its soluble form in Hodgkin's disease

, : ICAM-1 tissue overexpression associated with increased serum levels of its soluble form in Hodgkin's disease. British Journal of Haematology 84(1): 161-162

We investigated ICAM-1/CD54 tissue immunoreactivity and serum levels of its soluble form (sICAM-1) in patients with Hodgkin's disease (HD) at diagnosis. ICAM-1 was strongly expressed in involved tissues, and sICAM-1 serum levels were higher in HD (79 patients) than in controls (P < 0.01), and in patients with more advanced or more active disease (stages III + IV vI + II: P = 0.002; stage 'B' v 'A': P < 0.0001; 'bulky' disease v non-'bulky': P = 0.042). We suggest that tissue ICAM-1 overexpression leading to increase of circulating sICAM-1 may interfere with the lymphocyte adhesion machinery thus contributing to the well-known immune derangement of HD.


PMID: 8101721

DOI: 10.1111/j.1365-2141.1993.tb03040.x

Other references

Rogerson, M.; Cacho, I.; Jimenez-Espejo, F.; Reguera, M.I.; Sierro, F.J.; Martinez-Ruiz, F.; Frigola, J.; Canals, M., 2008: A dynamic explanation for the origin of the western Mediterranean organic-rich layers. The eastern Mediterranean sapropels are among the most intensively investigated phenomena in the paleoceanographic record, but relatively little has been written regarding the origin of the equivalent of the sapropels in the western Mediterranean,...

Postovit, N.V.; Shvets, G.L.; Bondarenko, S.N.; Kiĭchenko, I.A., 1989: Non-drug treatment of ulcers. On the basis of treatment of 131 patients with ulcer disease the efficacy was shown of the employment of electromagnetic radiation in the millimeter range and lasers. Using these non-drug methods it proved possible to reduce scarring time of duode...

Anderson, J.W.; Symonds-Tayler, R.; Webb, S., 2006: Investigating the fundamentals of IMRT decomposition using ten simple collimator models. The fundamentals of IMRT collimation have been studied using ten conceptual collimators. Spanning a range of complexities from the LINAC jaws alone to a full multi-leaf collimator (MLC), these collimators were designed with two abilities in mind:...

Langridge, D.F.; Goodman, R.D., 1982: Honeybee pollination of oilseed rape, cultivar Midas. In a trial on Brassica napus cv. Midas grown on dry land in northern Victoria, no increase in seed yield, oil content or germination was obtained from plots where honeybees and larger insects had access compared with plots enclosed in cages of 2.5...

Siodłak, D., 2015: α,β-Dehydroamino acids in naturally occurring peptides. α,β-Dehydroamino acids are naturally occurring non-coded amino acids, found primarily in peptides. The review focuses on the type of α,β-dehydroamino acids, the structure of dehydropeptides, the source of their origin and bioactivity. Dehydrop...

Vasilescu, V.O.teanu, A.S.anciu, G., 1982: Ways to increase the netto production in fruit tree growing. Productia vegatala: horticultura 31(8): 33-37

Eaton, B.T.; Ward, R.; Artsob, H., 1978: Aedes albopictus cells release a goose red blood cell agglutinin. The presence of a goose red blood cell (RBC) agglutinin (HA) in the culture medium of apparently uninfected cells of Aedes albopictus (Skuse) raised the possibility of contamination by an arbovirus. The HA sedimented in sucrose gradients between 1...

Mardynskii Y.S.; Andreev V.G.; Gulidov I.A., 1990: Using fast neutrons of a reactor in combination radiation therapy for disseminated laryngeal cancer. Meditsinskaya Radiologiya 35(9): 30

Greason, K.L.; Pochettino, A.; Sandhu, G.S.; Mathew, V., 2016: Transcatheter aortic valve insertion in the nonagenarian patient. Journal of Thoracic and Cardiovascular Surgery 150(3): 720-721

Nio Y.; Nitta N.; Tanaka A.; Kikuchi S.; Nakamoto K.; Henmi K., 1980: Clinical evaluation of prostaglandin f 2 alpha for the post operative ileus after major abdominal surgery. Of 77 patients, 40 were given PF[prostaglandin]F2.alpha. by i.v. drip infusion for the postoperative ileus, and 37 were given pantothenyl alcohol. The time between the operation and the 1st flatus of them was compared. The 1st flatus of the former...