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Immunohistochemical analysis of the oncoprotein c-erbB-2 expression in oral benign and malignant lesions

, : Immunohistochemical analysis of the oncoprotein c-erbB-2 expression in oral benign and malignant lesions. International Journal Of Oral & Maxillofacial Surgery. 27(3): 209-212, E

Thirty-seven samples of oral mucosa were analysed and divided histologically into groups of normal mucosa (6), hyperplastic lesions (6), dysplastic lesions (14), and squamous cell carcinoma (11). All lesions displayed some expression of c-erbB-2 but the distribution and intensity of expression varied strongly according to the differentiation. The lower the epithelial differentiation of the sample, the higher the expression of c-erbB-2 oncoprotein showing very strong staining in carcinoma samples. This suggests that in oral carcinoma, transformation might be related to c-erbB-2 interaction.


PMID: 9662015

DOI: 10.1016/s0901-5027(98)80012-x

Other references

Ohta, M.; Ina, K.; Kusuzaki, K.; Kido, N.; Arakawa, Y.; Kato, N., 1991: Cloning and expression of the rfe-rff gene cluster of Escherichia coli. We have cloned a 13 kb Escherichia coli DNA fragment which complemented the rfe mutation to recover the biosynthesis of E. coli O9 polysaccharide. Using Tn5 insertion inactivation, the rfe gene was localized at the 1.5 kb HindIII-EcoRI region flan...

Everett, T.; Parker, K.; Fish, J.; Pehora, C.; Budd, D.; Kelly, C.; Crawford, M.; Hayes, J., 2015: The construction and implementation of a novel postburn pruritus scale for infants and children aged five years or less: introducing the Toronto Pediatric Itch Scale. The authors' objectives were to design, refine, validate and implement a behavior-anchored postburn pruritus scale for children aged 5 years or less. We engaged a range of professionals involved in the care of children with burns. We used Q-m...

Brooke, L., 1978: Metal shelving for libraries. Hospital Libraries 3(4): 6-10

Connor, V., 2008: Contrast infusion sonography in the post-Essure setting. To compare contrast infusion sonogram (CIS) to hysterosalpingogram (HSG) for use as a 3-month confirmation test after Essure. Pilot study (Canadian Task Force classification II-2). Healthy women in an academic multispecialty group. Seventeen women...

Jaworski, J.N.; Ginsburg, B.C., 2002: THE BEATLES As A MODEL OF THE HUMAN BRAIN. The Beatles represent a potential teaching tool for the basic organization of the brain. Their worldwide success that continues unabated even 30 years after their last album has led to wide exposure to their works and individual characteristics, a...

Werminghaus, F., 1954: Results of the khellin treatment of spastic bronchitis in children. Monatsschrift für Kinderheilkunde 102(10): 450-451

Furova, T.N., 1967: The use of anticoagulants in the clinical course of internal disease. Meditsinskaia Sestra 26(5): 37-39

Kitchener, P.D.; Laing, N.G., 1993: Brachially innervated ectopic hindlimbs in the chick embryo. I. Limb motility and motor system anatomy during the development of embryonic behavior. The functional status of brachially innervated hindlimbs, produced by transplanting hindlimb buds of chick embryos in place of forelimb buds, was quantified by analyzing the number and temporal distribution of spontaneous limb movements. Brachiall...

Potekhin, S.A.; Melnik, T.N.; Popov, V.; Lanina, N.F.; Vazina, A.A.; Rigler, P.; Verdini, A.S.; Corradin, G.; Kajava, A.V., 2001: De novo design of fibrils made of short alpha-helical coiled coil peptides. Background: The alpha-helical coiled coil structures formed by 25-50 residues long peptides are recognized as one of Nature's favorite ways of creating an oligomerization motif. Known de novo designed and natural coiled coils use the lateral...

Anonymous, 1969: Masthead. Inorganic Chemistry 8(8): 1a-1a