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Immunohistochemical assessment of proliferation rate of breast carcinoma cells using Ki-67, MIB-1 and anti-PCNA monoclonal antibodies


, : Immunohistochemical assessment of proliferation rate of breast carcinoma cells using Ki-67, MIB-1 and anti-PCNA monoclonal antibodies. Polish Journal of Pathology 47(4): 189-194

MIB-1, Ki-67 and PCNA scores in infiltrating ductal NOS breast carcinomas were compared. The correlation between MIB-1, Ki-67 and PCNA indices and several clinicopathological factors that have prognostic significance in breast cancer was also assessed. The mean Ki-67, MIB-1 and PCNA indices were 13.4%, 19.4%, 27.6%, respectively. Significant positive linear correlation was found only between Ki-67 and MIB-1 indices. PCNA score did not correlate with Ki-67 and MIB-1 indices. The significant correlation between Ki-67 and MIB-1 scores and histological grade was found. There was no correlation between Ki-67 and MIB-1 indices and axillary lymph node status or tumor diameter. The results suggest that MIB-1 antibody is an excellent tool for assessment of proliferative rate of breast cancer cells in paraffin sections.

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PMID: 9097711


Other references

Bachewich, C.; Heath, I.B., 1999: Cytoplasmic migrations and vacuolation are associated with growth recovery in hyphae of Saprolegnia, and are dependent on the cytoskeleton. Hyphae of S. ferax recovered from intracellular acidification with variable degrees of apical vacuolation and migration of cytoplasm out of the apex, prior to apical refilling and resumption of growth. The response was not due to alkalinization, b...

Sato, M.; Fujiura, H.; Imai, K.; Murata, T., 1980: Effect of sodium copper chlorophyllin on lipid per oxidation 4. the anti oxidative action of copper chlorins. The relationship between the antioxidative action of sodium copper chlorophyllin (Cu-Chl-Na) and its chemical structure was examined. By the aerobic incubation of Cu-Chl-Na in aqueous solution, the spectral absorbances of the solution at Soret (40...

Chatkupt, S.; Ruzicka, P.O.; Lastra, C.R., 1993: Myelomeningocele, spinal arteriovenous malformations and epidermal nevi syndrome: a possible rare association?. A 20-year-old woman with myelomeningocele presented with acute right-ear pain and right hemiplegia which improved, but then progressively deteriorated. Surgery, after MRI, revealed a large arteriovenous malformation (AVM) involving the right side...

O'Toole, P.A.; Morris, A.I., 1995: Heliox treatment for pneumatosis cystoides coli. Lancet 346(8988): 1498-1499

Anonymous, 1982: A bibliography on natural resources and environmental conflict: management strategies and processes. A complementary publication to Bibliography No. 64, divided into 6 sections: Overview of environmental conflict management; Negotiation and mediation; Alternative methods and processes; Dynamics and processes of conflict; Techniques and methods fo...

Maekawa, M.; Mashimoto, Y.; Sugie, T.; Hara, T.; Watanabe, T., 1964: Case Of Pulmonary Resection For Aspergillosis Forming A Fungs Ball. Kyobu Geka. Japanese Journal of Thoracic Surgery 17: 629-632

Harke, A.B.; Sigamani, K.; Thukkaram, C.; Ramamurthy, M.; Sekar, M., 2016: Massive Ovarian Oedema- A Case Report. Massive ovarian oedema is defined by WHO as formation of tumour like enlargement of one or both ovaries by oedema fluid. We report a case of a 18-year-old unmarried girl who presented with three months amenorrhoea and left sided lower abdominal pa...

Chiou, R.K.; Vessella, R.L.; Elson, M.K.; Clayman, R.V.; Gonzalez-Campoy, J.M.; Klicka, M.J.; Shafer, R.B.; Lange, P.H., 1985: Localization of human renal cell carcinoma xenografts with a tumor-preferential monoclonal antibody. We previously described an immunoglobulin G1 monoclonal antibody (UMVA-RCC-A6H) that is highly reactive with human renal cell carcinoma (RCC) and has little cross-reactivity to other cell types both normal and malignant. In efforts detailed herein...

Stixrude Lars; Wentzcovitch Renata M., 2002: Thermoelasticity of the lower mantle from first principles; implications for the origin of lateral heterogeneity. Eos, Transactions, American Geophysical Union: 7, Suppl., Pages F624. 2002.

Barker R.J.; Smith J.; Lai P.F., 1980: The culture of the microsporidian parasites nosema algerae and nosema eurytremae in vertebrate cells. Journal of Protozoology 27(3): 55A-56A