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Immunohistochemical changes in the anterior olfactory nucleus of the developing rat

, : Immunohistochemical changes in the anterior olfactory nucleus of the developing rat. Developmental Psychobiology. 31(3): 181-192,.

The anterior olfactory nucleus (AON) is located caudal to the olfactory bulb in the olfactory peduncle. Although this important structure is involved in the bilateral coordination of olfactory information, relatively little is known about its development, structure, or function. The present report details results from an immunohistochemical examination of specific neuronal (microtubule-associated protein-2; MAP2, calbindin D28-k, neuropeptide-Y; NPY) and glial (astrocytes; glial fibrillary-associated protein, or GFAP, oligodendrocytes; RIP) populations in postnatal Days 10, 20 and 30 rats. MAP2-immunoreactivity (-ir), was present throughout the AON, although most dense in the outer plexiform layer. Increases in labeling occurred from Day 10 to Day 30, reflecting the maturation of dendritic processes. Both temporal and regional differences in expression were found with the two neuronal markers. For example, although substantial numbers of calbindin-ir cells were observed as early as Day 10, relatively few cells exhibited NPY-ir. An apparent decline in the number of stained figures was observed from days 20-30 with both markers. Most cells exhibiting calbindin- or NPY-ir were found in the inner half of the cellular zone of AON, GFAP-ir was localized mainly to the subependymal zone and the lateral olfactory tract (LOT) at Day 10, with successive increases in staining the cellular and plexiform layers at Days 20 and 30. Oligodendrocyte-ir was restricted to the anterior commissure and the LOT at Day 10, with dramatic increases in labeling of the cellular and plexiform layers observed by Days 20 and 30. These results represent some of the first analyses of the maturation of specific cellular phenotypes within this large neural region.


PMID: 9386920

DOI: 10.1002/(sici)1098-2302(199711)31:3<181::aid-dev3>;2-o

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Arroyo, L.; Carreras, R.; Valent, D.; Peña, R.; Mainau, E.; Velarde, A.; Sabrià, J.; Bassols, A., 2016: Effect of handling on neurotransmitter profile in pig brain according to fear related behaviour. NlmCategory="UNASSIGNED">Chemical neurotransmitters (NT) are principal actors in all neuronal networks of animals. The central nervous system plays an important role in stress susceptibility and organizes the response to a stressful s...

Halliwell,, A.H.lliwell, N., 1991: Hydrolysis of native and derived forms of cellulose: their significance in cellulase determinations. Agrofoodindustry hi tech 2(5): 21-27

Peele D.B.; Baron S.P., 1987: Repeated acquisition of radial maze performance a novel procedure for assessing chemically induced disruption of associative learning. Society for Neuroscience Abstracts 13(2): 837

Nagai S.; Fujimura N.; Hirata T.; Izumi T., 1985: Differentiation between idiopathic pulmonary fibrosis and interstitial pneumonia associated with collagen vascular diseases by comparison of the ratio of okt 4 positive cells and okt 8 positive cells in balf t lymphocytes. Idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia associated with collagen vascular disease have been shown to be difficult to differentiate by clinical, roentgenological, pathological and immunological findings. We have applied the a...

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Apuzzo, M.L.J.; Liu, C.Y.; Sullivan, D.; Faccio, R.A., 2008: Surgery of the human cerebrum--a collective modernity. Safe and beneficial surgery of the human cerebrum is arguably one of mankind's most notable achievements and one of the great testimonials to human creativity, intelligence, and character. In many ways, it is a testimony to the climates of ci...

Thomas, L.; Needham, T.; Earl, U.; Elsaify, W., 2015: Management of adrenocortical carcinoma. Anz Journal of Surgery: -

Vimond Laboudigue A.; Prost R., 1995: Comparative study of hectorite- and vermiculite-decylammonium complexes by means of infrared and Raman spectrometry. Clay Minerals: , Pages 337-352. 1995.

Friedrich, P., 1963: Comparative Description Of 2 Cases Of Delusion. A Contribution To The Differential Diagnosis Of Delusion. Acta Societatis Medicorum Upsaliensis 68: 84-102