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Immunohistochemical characteristics and ultrastructural features of the cervix squamous cell carcinoma of the ectocervical and endocervical (cambial cell or metaplastic) genesis


, : Immunohistochemical characteristics and ultrastructural features of the cervix squamous cell carcinoma of the ectocervical and endocervical (cambial cell or metaplastic) genesis. Arkhiv Patologii 58(2): 13-21

Among 199 invasive squamous cell carcinomas immunophenotype of ectocervical carcinoma (true squamous cell one) was found in 18 tumors. Immunophenotype of metaplastic, endocervical squamous cell carcinoma was established in 181 cases. There was a pronounced expression of cytokeratins N 1, 2, 10, 14 and negative of weak expression of N 8 and 17. Ultrastructural features of this carcinoma type were desmosomes on microprocesses, abundant bundles of cytoplasmic tonofibrils.

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